https://scholars.lib.ntu.edu.tw/handle/123456789/543873
標題: | Increased risk of depressive disorder following diagnosis with bladder pain syndrome/interstitial cystitis | 作者: | Keller J.J. SHIH-PING LIU Lin H.-C. |
關鍵字: | bladder pain syndrome/interstitial cystitis; depressive disorder; epidemiology | 公開日期: | 2013 | 卷: | 32 | 期: | 5 | 起(迄)頁: | 467-471 | 來源出版物: | Neurourology and Urodynamics | 摘要: | Aim Bladder pain syndrome/interstitial cystitis (BPS/IC) is a chronic pain syndrome of unknown etiology that primarily affects women. Using a longitudinal follow-up design, this study aimed to examine the risk of depressive disorder (DD) among women with BPS/IC compared to the general population during a 1-year period following their diagnosis. Method This study used data from the Taiwan "Longitudinal Health Insurance Database." A total of 832 patients with BPS/IC were included in the study group and 4,160 matched non-BPS/IC enrollees were included as the comparison group. Each patient (n = 4,992) was individually tracked for a 1-year period to identify those who subsequently received a diagnosis of DD. Cox proportional hazards regressions (stratified by age group and the index year) were used to estimate the risk of subsequent DD following a diagnosis of BPS/IC. Results We found that during the 1-year follow-up, the incidence rate of DD was 4.69 (95% CI: 3.38-6.34) per 100 person-years in patients with BPS/IC and 0.94 (95% CI: 0.68-1.27) per 100 person-years in comparison patients. The hazard ratio (HR) of DD during the 1-year follow-up period for patients with BPS/IC was 5.06 (95% CI: 3.21-7.96, P < 0.001) that of comparison patients after adjusting for patient monthly income, geographic location, and urbanization level. The adjusted HR for DD associated with BPS/IC was 10.33 for patients aged between 40 and 49 (95% CI: 3.68-29.04). Conclusion Our study demonstrated that there is an increased risk for being diagnosed with DD during the first year subsequent to being diagnosed with IC/PBS. Copyright ? 2012 Wiley Periodicals, Inc. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84879410367&doi=10.1002%2fnau.22316&partnerID=40&md5=f8e80b91318ffb106d9174307b01e674 https://scholars.lib.ntu.edu.tw/handle/123456789/543873 |
ISSN: | 0733-2467 | DOI: | 10.1002/nau.22316 | SDG/關鍵字: | adult; aged; article; cystalgia; depression; female; follow up; geography; human; income; interstitial cystitis; major clinical study; male; Taiwan; urbanization; adolescent; case control study; Cystitis, Interstitial; Depressive Disorder; incidence; Kaplan Meier method; middle aged; proportional hazards model; psychology; risk factor; time; young adult; Adolescent; Adult; Aged; Case-Control Studies; Cystitis, Interstitial; Depressive Disorder; Female; Follow-Up Studies; Humans; Incidence; Kaplan-Meier Estimate; Middle Aged; Proportional Hazards Models; Risk Factors; Taiwan; Time Factors; Young Adult |
顯示於: | 醫學系 |
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