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  1. NTU Scholars
  2. 醫學院
  3. 醫學系
Please use this identifier to cite or link to this item: https://scholars.lib.ntu.edu.tw/handle/123456789/545831
Title: Appendectomy increased the risk of ischemic heart disease
Authors: Chen C.-H.
Tsai M.-C.
Lin H.-C.
Lee H.-C.
Lee, Cha-Ze 
Chung S.-D.
Keywords: Appendectomy; Appendix; Ischemic heart disease
Issue Date: 2015
Publisher: Academic Press Inc.
Journal Volume: 199
Journal Issue: 2
Start page/Pages: 435-440
Source: Journal of Surgical Research
Abstract: 
Background Although the appendix may not be considered vital, recent studies have noted adverse health consequences after appendectomy. This study aimed to use a population-based data set to explore whether appendectomy increases the risk for subsequent ischemic heart disease (IHD) in a 3-y follow-up period. Materials and methods This study used data from the Longitudinal Health Insurance Database 2000 in Taiwan. The study cohort included 5413 patients who underwent appendectomies. The comparison cohort was selected by randomly recruiting 16,239 enrollees matched with the study group in terms of sex, age, hypertension, hyperlipidemia, and diabetes. Each individual was tracked for 3 y to identify whether he and/or she developed IHD during the follow-up period. Cox proportional hazard regressions were performed for analysis. Results During a 3-y follow-up, 196 (3.62%) and 375 (2.31%) IHD incidents developed in the study and the comparison cohorts, respectively. For adults aged ?18 y, experiencing an appendectomy was independently associated with a 1.54-fold increased risk of IHD during the 3 y of follow-up (95% CI = 1.29-1.84). The association persisted in further analyses stratified by age. Conclusions There is an increased risk of subsequent IHD within 3 y after appendectomy, and this underscores the need for more serious clinical decision-making in removing the appendix. Regular monitoring for IHDs is also recommended for patients who have undergone an appendectomy. ? 2015 Elsevier Inc.
URI: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84947869674&doi=10.1016%2fj.jss.2015.06.049&partnerID=40&md5=6a137c9b573822acd4436a4377de0d85
https://scholars.lib.ntu.edu.tw/handle/123456789/545831
ISSN: 0022-4804
DOI: 10.1016/j.jss.2015.06.049
SDG/Keyword: adult; adverse effects; appendectomy; female; human; male; middle aged; Myocardial Ischemia; retrospective study; risk; Taiwan; young adult; Adult; Appendectomy; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Retrospective Studies; Risk; Taiwan; Young Adult
[SDGs]SDG3
Appears in Collections:醫學系

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臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

總館學科館員 (Main Library)
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開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

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