https://scholars.lib.ntu.edu.tw/handle/123456789/545864
標題: | Effect of hepatitis C antibody screening in blood donors on post‐transfusion hepatitis in Taiwan | 作者: | JIN-TOWN WANG WANG T.-H. LIN J.-T. Lee, Cha-Ze JIN-CHUAN SHEU DING-SHINN CHEN |
公開日期: | 1995 | 卷: | 10 | 期: | 4 | 起(迄)頁: | 454-458 | 來源出版物: | Journal of Gastroenterology and Hepatology | 摘要: | A national screening programme for antibody to hepatitis C virus (HCV) in blood donors in Taiwan began in July 1992 using a second?generation immunoassay. To study the impact of this screening on post?transfusion hepatitis in Taiwan, a prospective study on post?transfusion hepatitis, that was started in 1987, was continued. As of June 1994, 245 patients who received a blood transfusion after July 1992 had completed a follow?up period for more than 6 months post?transfusion. Of them, seven (2.8%) recipients developed acute post?transfusion hepatitis. The hepatitis in six cases could not be attributed to infection by hepatitis A, B, C, D, E viruses or cytomegalovirus (CMV) or Epstein?Barr virus (EBV). The remaining patient seroconverted to both IgG and IgM anti?CMV. All seven patients recovered in 6 months without development of chronicity, and the mean peak alanine aminotransferase level was lower compared with that of the cases before anti?HCV screening (i.e. pre?July 1992). These results indicate that the current anti?HCV screening has effectively interrupted HCV transmission through blood transfusion in Taiwan. Copyright ? 1995, Wiley Blackwell. All rights reserved |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029089762&doi=10.1111%2fj.1440-1746.1995.tb01599.x&partnerID=40&md5=45160f0b251692d022c3933a485a4f24 https://scholars.lib.ntu.edu.tw/handle/123456789/545864 |
ISSN: | 0815-9319 | DOI: | 10.1111/j.1440-1746.1995.tb01599.x | SDG/關鍵字: | hepatitis C antibody; adult; aged; article; blood transfusion; donor; female; hepatitis; hepatitis C; human; major clinical study; male; priority journal; screening; seroconversion; Taiwan; virus transmission |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。