https://scholars.lib.ntu.edu.tw/handle/123456789/547835
標題: | The effects of continuous epidural analgesia on Doppler velocimetry of uterine arteries during different periods of labour analgesia | 作者: | LI-KUEI CHEN Lin C.J. CHI-HSIANG HUANG Wang M.H. PEI-LIN LIN CHIEN-NAN LEE WEI-ZEN SUN |
公開日期: | 2006 | 出版社: | Oxford University Press | 卷: | 96 | 期: | 2 | 起(迄)頁: | 226-230 | 來源出版物: | British Journal of Anaesthesia | 摘要: | Background. The transient effects of epidural bupivacaine 0.25-0.5% on the Doppler velocimetry of umbilical and uterine arteries had been reported, but the effects of continuous lower dose epidural bupivacaine (0.05-0.1%) infusion for labour analgesia have never been reported. In this study, we evaluated the effects of continuous epidural bupivacaine 0.075% on the Doppler velocimetry of uterine arteries. Methods. Twenty pregnant women for labour analgesia received continuous epidural bupivacaine 0.075% infusion. We used a 4-MHz continuous-wave Doppler probe (Multigon 500A) with a 200 Hz thump filter to detect uterine blood flow velocity. We recorded the velocimetry data for uterine relaxation and contraction during five time periods: Pre-epidural insertion, 1, 2, and 4 h post-epidural infusion, and after delivery of fetus. Results. Our data showed that the velocimetric indices of uterine vascular resistance were significantly increased 1, 2, and 4 h after epidural infusion when compared with the pre-epidural level; these returned to the baseline after delivery. Conclusion. Continuous epidural analgesia with bupivacaine 0.075% increases the resistance of uterine artery and therefore possibly reduces the uterine blood flow. ? The Board of Management and Trustees of the British Journal of Anaesthesia 2005. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-31744447987&doi=10.1093%2fbja%2faei311&partnerID=40&md5=eca43ff7d173ca87335530de8c418ed8 https://scholars.lib.ntu.edu.tw/handle/123456789/547835 |
ISSN: | 0007-0912 | DOI: | 10.1093/bja/aei311 | SDG/關鍵字: | bupivacaine; lidocaine; article; bradycardia; childbirth; clinical article; continuous epidural anesthesia; controlled study; Doppler flowmetry; drug dose regimen; drug efficacy; drug infusion; female; fetus; fetus disease; filter; human; hypotension; hypovolemia; medical record; obstetric anesthesia; postoperative period; pregnant woman; preoperative period; priority journal; uterine artery; uterus blood flow; uterus contraction; uterus relaxation; vascular resistance |
顯示於: | 醫學系 |
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