Antenatal diagnosis of congenital hepatoblastoma in utero
Journal
Ultrasound in Obstetrics and Gynecology
Journal Volume
16
Journal Issue
1
Pages
94-97
Date Issued
2000
Author(s)
Abstract
A fetus with a huge hepatic tumor was detected by sonography at 36 weeks of gestation. The mass appeared as a single, solid and polylobular tumor located in the right lobe of the liver. Foci of hemorrhage, necrosis and some tiny calcifications were seen. The adjacent right kidney appeared normal but was displaced. The right adrenal gland was not visualized. Three-dimensional power Doppler sonography further depicted the corresponding vascular anatomy of the tumor, including its vascularization pattern and blood supply. The tumor was situated to the right of the umbilical vein and portal sinus, possibly deriving its blood supply from the portal circulation. The fundamental findings suggested the diagnosis of hepatoblastoma by exclusion of other possibilities. The baby was delivered by Cesarean section at 36 weeks' gestation, due to signs of fetal distress. Unfortunately, hypotension, tachycardia, and tachypnea developed shortly after birth. Surgical intervention was performed, but intractable bleeding occurred intra-operatively. The infant died at 6 days of age. Autopsy confirmed the diagnosis of hepatoblastoma. We believe this is the first reported case of the antenatal diagnosis of congenital hepatoblastoma.
SDGs
Other Subjects
adult; article; calcification; case report; cesarean section; differential diagnosis; Doppler echography; echography; female; fetus distress; hepatoblastoma; human; portal vein blood flow; prenatal diagnosis; priority journal; Adult; Female; Fetal Diseases; Hepatoblastoma; Humans; Liver Neoplasms; Pregnancy; Ultrasonography, Doppler; Ultrasonography, Prenatal
Type
journal article