https://scholars.lib.ntu.edu.tw/handle/123456789/548545
標題: | A nine-year follow-up study of sleep patterns and mortality in community-dwelling older adults in Taiwan | 作者: | HSI-CHUNG CHEN Su T.-P. Chou P. |
關鍵字: | Insomnia; Older adults; Sleep duration; Sleep pattern; Use of hypnotics | 公開日期: | 2013 | 卷: | 36 | 期: | 8 | 起(迄)頁: | 1187-1198 | 來源出版物: | Sleep | 摘要: | Study Objectives: To simultaneously explore the associations between mortality and insomnia, sleep duration, and the use of hypnotics in older adults. Design: A fixed cohort study. Setting: A community in Shih-Pai area, Taipei, Taiwan. Participants: A total of 4,064 participants over the age of 65 completed the study. Intervention: N/A. Measurements and Results: Insomnia was classified using an exclusionary hierarchical algorithm, which categorized insomnia as "no insomnia," "subjective poor sleep quality," "Pittsburgh Sleep Quality Index > 5 insomnia," "1-month insomnia disorder," and "6-month insomnia disorder." The main outcome variables were 9-year all-cause mortality rates. In the all-cause mortality analyses, when hypnotic use, depressive symptoms and total sleep time were excluded from a proportional hazards regression model, subjects with "Pittsburgh Sleep Quality Index > 5 insomnia" had a higher mortality risk (HR: 1.21, 95% CI: 1.01-1.45). In the full model, frequent hypnotic use and long sleep duration predicted higher mortality rates. However, the increased mortality risk for subjects with "Pittsburgh Sleep Quality Index > 5 insomnia" was not observed in the full model. On the contrary, individuals with a 6-month DSM-IV insomnia disorder had a lower risk for premature death (HR: 0.64, 95% CI: 0.43-0.96). Conclusions: Long sleep duration and frequent hypnotics use predicted an increased mortality risk within a community-dwelling sample of older adults. The association between insomnia and mortality was affected by insomnia definition and other parameters related to sleep patterns. |
URI: | 2-s2.0-84881126820 https://scholars.lib.ntu.edu.tw/handle/123456789/548545 |
ISSN: | 1618105 | DOI: | 10.5665/sleep.2884 | SDG/關鍵字: | hypnotic agent; aged; article; cardiovascular risk; depression; DSM-IV; female; follow up; human; insomnia; major clinical study; male; mortality; night sleep; Pittsburgh Sleep Quality Index; priority journal; sleep parameters; sleep pattern; sleep quality; sleep time; Taiwan; Insomnia; older adults; sleep duration; sleep pattern; use of hypnotics; Aged; Algorithms; Female; Follow-Up Studies; Humans; Hypnotics and Sedatives; Male; Mortality; Proportional Hazards Models; Severity of Illness Index; Sleep; Sleep Initiation and Maintenance Disorders; Taiwan |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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