https://scholars.lib.ntu.edu.tw/handle/123456789/548851
標題: | Changes in ticlopidine utilization pattern after educational intervention | 作者: | Yang Y.-H.K. Chen L.-C. KIN-WEI CHAN Lai M.-L. |
關鍵字: | Antiplatelet agent; Drug utilization evaluation; Prescribing behavior; Ticlopidine | 公開日期: | 1999 | 卷: | 51 | 期: | 5 | 起(迄)頁: | 347-358 | 來源出版物: | Chinese Pharmaceutical Journal | 摘要: | Background: Ticlopidine is used for the prophylaxis of thrombotic disorders. A disadvantage of its use is the development of serious adverse hematological effects, especially neutropenia. Therefore, prescribing of ticlopidine was evaluated before and after educational intervention in a medical center. Objective: To evaluate the effects of an educational intervention program on the appropriateness of ticlopidine usage at the National Cheng Kung University Hospital. Methods: A structured Drug Utilization Evaluation (DUE) program was conducted with educational intervention. The medical records corresponding to the designated periods were selected from a computerized database. A clinical pharmacist evaluated the medical records, applying the DUE criteria, before and after intervention. Results: Study subjects included 243 patients before intervention and 112 patients after intervention who received ticlopidine. Ticlopidine was mostly prescribed for patients with cerebrovascular stroke both before and after intervention (81.5 % and 80.4 %). The most frequently prescribed dose was 200 mg per day in the two periods (55.6 % and 60.9 %). After intervention, the concomitant use of aspirin and ticlopidine decreased significantly (P < 0.001). Compliance with usage guidelines (P = 0.005) and hematological monitoring (P = 0.016-0.041) improved significantly after intervention. Conclusion: The authors conclude that educational intervention by pharmacists may have a significant influence on the prescribing pattern of ticlopidine. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0033390573&partnerID=40&md5=97f56d1db9e034731bf06c13f4d760ce https://scholars.lib.ntu.edu.tw/handle/123456789/548851 |
ISSN: | 1016-1015 | SDG/關鍵字: | acetylsalicylic acid; licodin; ticlopidine; unclassified drug; adult; aged; article; cerebrovascular accident; drug utilization; female; health education; human; major clinical study; male; neutropenia; patient compliance; prescription; thrombosis |
顯示於: | 腫瘤醫學研究所 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。