TRPML Cation Channels in Inflammation and Immunity
Journal
Frontiers in Immunology
Journal Volume
11
Pages
225
Date Issued
2020
Author(s)
Abstract
Although our understanding of the functional roles of TRPML channels in inflammation and immunity is still in its infancy, a few interesting findings have been made in the past years, encouraging further and more detailed work on the role of TRPMLs, e.g., in intracellular trafficking and release of chemokines, cytokines, or granzyme B, or in phagocytosis and bacterial toxin and virus trafficking through the endolysosomal machinery.
SDGs
Type
review