Inhibiting autophagy potentiates the antitumor efficacy of Euphorbia royleana for canine mammary gland tumors
Journal
BMC Veterinary Research
Journal Volume
16
Journal Issue
1
Date Issued
2020
Author(s)
Huang, Y.-Y.
Chen, C.-H.
Hsu, C.-H.
Kuo, T.-Y.
Liu, C.-C.
Liao, A.T.-C.
Liao, A.T.-C.
Lin, C.-S.
SDGs
Other Subjects
bafilomycin; caspase 3; caspase 9; lactate dehydrogenase; microtubule associated protein 1; mitomycin; protein Bax; protein bcl 2; protein kinase B; protein p53; PUMA protein; plant extract; animal cell; animal experiment; animal model; animal tissue; antineoplastic activity; antiproliferative activity; apoptosis; Article; autophagy (cellular); breast tumor; cell cycle arrest; cell growth; cell proliferation; cell survival; cell viability; cell viability assay; controlled study; cytotoxicity; cytotoxicity assay; Euphorbia; Euphorbia royleana; flow cytometry; human; human cell; IC50; immunoblotting; mitochondrial membrane potential; mouse; MTT assay; nonhuman; protein expression; tumor growth; Western blotting; animal; autophagy; cell cycle checkpoint; cell line; chemistry; Chlorocebus aethiops; dog; dog disease; drug effect; Euphorbia; experimental mammary neoplasm; female; nude mouse; Vero cell line; Animals; Apoptosis; Autophagy; Cell Cycle Checkpoints; Cell Line; Chlorocebus aethiops; Dog Diseases; Dogs; Euphorbia; Female; Mammary Neoplasms, Animal; Mice, Nude; Plant Extracts; Vero Cells
Type
journal article