NIACE score refines the overall survival of hepatocellular carcinoma by Barcelona clinic liver cancer staging
Journal
Journal of Gastroenterology and Hepatology (Australia)
Journal Volume
34
Journal Issue
12
Pages
2179-2186
Date Issued
2019
Author(s)
Abstract
Background and Aim: The NIACE score provides prognostic values for hepatocellular carcinoma (HCC) in European studies. We aim to evaluate the prognostic value of the NIACE score in Asian patients. Methods: Patients with HCC were retrospectively enrolled from a tertiary medical center in Taiwan during 2009–2014, and their clinical information were collected. The NIACE score was calculated according to the Nodular numbers, tumor Infiltration, Alpha-fetoprotein level, Child–Pugh score, and Eastern Cooperative Oncology Group score. The prognostic values of NIACE score for overall survival according to individual treatment and the Barcelona clinic liver cancer (BCLC) staging were analyzed. Results: A total of 468 patients were included with a median follow-up of 30?months. A greater NIACE score correlated with lower median survival and higher BCLC staging. Regardless of treatment modalities, NIACE scores (0, 1–1.5, 2.5–3, and 4–7) significantly predicted survival between groups (log–rank P?
SDGs
Other Subjects
alpha fetoprotein; sorafenib; adult; aged; alpha fetoprotein blood level; Article; Asian; cancer patient; cancer prognosis; cancer staging; cancer surgery; cancer survival; chemoembolization; Child Pugh score; female; follow up; human; liver cell carcinoma; major clinical study; male; multimodality cancer therapy; NIACE score; overall survival; priority journal; radiofrequency ablation; retrospective study; scoring system; survival prediction; systemic therapy; Taiwan; epidemiology; Kaplan Meier method; liver cell carcinoma; liver tumor; middle aged; mortality; pathology; predictive value; procedures; prognosis; severity of illness index; very elderly; young adult; Adult; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Predictive Value of Tests; Prognosis; Retrospective Studies; Severity of Illness Index; Taiwan; Young Adult
Publisher
Blackwell Publishing
Type
journal article