Altered circadian rhythm of blood pressure in patients with cerebral stroke
Journal
American Journal of Noninvasive Cardiology
Journal Volume
6
Journal Issue
1
Pages
62-65
Date Issued
1992
Author(s)
Abstract
The characteristics of blood pressure (BP) patterns in patients with cerebrovascular accident have not been well studied. Nineteen patients with acute stroke received 24-hour noninvasive ambulatory BP monitoring during the acute and the late stages of stroke. Fourteen patients had past history of hypertension. In the acute stage, the differences between daytime BP averages (147/95 ± 19/11 mm Hg) and nighttime averages (145/92 ± 13/9 mm Hg) were not statistically significant in patients with past history of hypertension (p > 0.5 for systolic BP; p > 0.1 for diastolic BP). In patients without history of hypertension, the daytime BP average (127/89 ±7/13 mm Hg) was significantly higher than the nighttime average (118/80 ±2/15 mm Hg) in systole (p < 0.05), but not in diastole (p > 0.05). During the late stage of stroke, the differences between daytime BP averages ( 143/95 ± 24/13 mm Hg) and nighttime BP averages (135/96 ± 19/12 mm Hg) were not statistically significant for the hypertensive group (p > 0.05 for both systolic and diastolic BP). In conclusion, hypertensive patients with cerebrovascular accident did not exhibit the nocturnal fall of BP both in the acute and late stages of the disease. The same phenomenon was observed for the diastolic BP in patients without history of hypertension. The mechanisms of the loss of circadian change of BP and its clinical implications are the interesting topics for further studies.
SDGs
Type
journal article