Value of Ga-67 SPECT in monitoring the effects of therapy in invasive aspergillosis of the sphenoid sinus
Journal
Clinical Nuclear Medicine
Journal Volume
24
Journal Issue
12
Pages
938-941
Date Issued
1999
Author(s)
KAI-YUAN TZEN
Yen T.-C.
Lin K.-J.
Abstract
PURPOSE: We report a case of invasive sphenoid sinus aspergillosis clinically presenting as a pituitary mass. METHODS: After exploration via the trans-sphenoidal approach and subsequent treatment with amphotericin-B, Ga-67 brain SPECT was performed twice to monitor the therapeutic effect. RESULTS: Three months after antifungal treatment, Ga-67 brain SPECT showed partial resolution of the lesion in the sella turcica region. The patient continued with fluconazole treatment for another 2 months and received another Ga-67 brain SPECT, which showed complete clearing of the previous lesion. CONCLUSION: Ga-67 brain SPECT may play a potentially useful role in monitoring the therapeutic effect of treatment of invasive sphenoid sinus aspergillosis.
SDGs
Type
journal article