https://scholars.lib.ntu.edu.tw/handle/123456789/553655
標題: | Systemic lupus erythematosus is associated with poor outcome after acute myocardial infarction | 作者: | Ke S.-R. Liu C.-W. YEN-WEN WU Lai K.R. Wu C.-Y. Lin J.-W. Chan C.-L. Pan R.-H. |
關鍵字: | Acute myocardial infarction; Mortality; Prolonged hospitalization; Systemic lupus erythematosus | 公開日期: | 2019 | 卷: | 29 | 期: | 12 | 起(迄)頁: | 1400-1407 | 來源出版物: | Nutrition, Metabolism and Cardiovascular Diseases | 摘要: | Background: Systemic lupus erythematosus (SLE) is associated with a higher risk of cardiovascular disease. However, it is not clear whether or not SLE is associated with poor outcomes after acute myocardial infarction (AMI). Methods and results: Using the Taiwan National Health Insurance Database, we identified the SLE group as patients with AMI who have a concurrent discharge diagnosis of SLE. We also selected an age-, sex-, hospital level-, and admission calendar year-matched non-SLE group at a ratio of 1:3 from the total non-SLE group. One hundred fifty-one patients with SLE, 113,791 patients without SLE, and 453 matched patients without SLE were admitted with a diagnosis of AMI. Patients with SLE were significantly younger, predominantly female, and more likely to have chronic kidney disease than those without SLE. The in-hospital mortality rates were 12.6%, 9.0%, and 4.2% in the SLE, total non-SLE, and matched non-SLE groups, respectively. The in-hospital mortality was significantly higher in the SLE group than in the total non-SLE group (OR = 1.98; 95% CI = 1.2–3.26) and the matched non-SLE group (mortality OR = 2.20; 95% CI = 1.06–4.58). In addition, the SLE group was associated with a borderline significant risk of prolonged hospitalization when compared with the non-SLE group. Conclusion: SLE is associated with a higher risk of in-hospital mortality and a borderline significantly higher risk of prolonged hospitalization after AMI. ? 2019 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/553655 | ISSN: | 0939-4753 | DOI: | 10.1016/j.numecd.2019.08.006 | SDG/關鍵字: | acute heart infarction; adult; aged; Article; chronic kidney failure; comparative study; controlled study; coronary artery bypass graft; coronary stenting; disease association; extracorporeal oxygenation; female; health care cost; hemodialysis; hospital admission; hospital discharge; hospital mortality; hospitalization; human; major clinical study; male; middle aged; national health insurance; priority journal; prognosis; sex difference; systemic lupus erythematosus; transluminal coronary angioplasty; young adult; age; chronic kidney failure; epidemiology; factual database; heart infarction; hospital mortality; length of stay; mortality; prognosis; risk assessment; risk factor; sex factor; systemic lupus erythematosus; Taiwan; time factor; Adult; Age Factors; Aged; Databases, Factual; Female; Hospital Mortality; Humans; Length of Stay; Lupus Erythematosus, Systemic; Male; Middle Aged; Myocardial Infarction; Prognosis; Renal Insufficiency, Chronic; Risk Assessment; Risk Factors; Sex Factors; Taiwan; Time Factors; Young Adult |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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