https://scholars.lib.ntu.edu.tw/handle/123456789/554005
標題: | A 2-year follow-up of swallowing function after radiation therapy in patients with nasopharyngeal carcinoma | 作者: | YEUN-CHUNG CHANG SSU-YUAN CHEN Ting L.-L. STEVEN SHINN-FORNG PENG Wang T.-C. TYNG-GUEY WANG |
公開日期: | 2011 | 卷: | 92 | 期: | 11 | 起(迄)頁: | 1814-1819 | 來源出版物: | Archives of Physical Medicine and Rehabilitation | 摘要: | Objective: To evaluate over a 2-year period the serial swallowing function of patients with nasopharyngeal carcinoma (NPC) after completing radiotherapy (RT). Design: Prospective longitudinal follow-up. Setting: University hospital. Participants: Patients with NPC (N=76) referred for RT: 53 of them at 1 year after RT, and 23 at 2 years after RT. Interventions: Not applicable. Main Outcome Measures: Participants completed a questionnaire and had a video-recorded fluoroscopic swallowing study before RT and 1 month, 1 year, and 2 years after RT. Results: The highest incidence of dysphagia symptoms and retropharyngeal soft tissue swelling occurred in the first month after RT and decreased over time. Pharyngeal transit time was prolonged continuously up to 1 year after RT. Epiglottic vallecular stasis and pharyngeal mucosal coating were worst in the first month after RT and stable afterwards. Aspiration was uncommon during the first 2 years after RT. Conclusions: At a 2-year follow-up after RT, patients with NPC had a progressively increasing pharyngeal transit time, although the subjectively identified symptoms of dysphagia decreased after the first month after RT. ? 2011 American Congress of Rehabilitation Medicine. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/554005 | ISSN: | 0003-9993 | DOI: | 10.1016/j.apmr.2011.06.008 | SDG/關鍵字: | cisplatin; epirubicin; fluorouracil; folinic acid; mitomycin; article; aspiration; cancer radiotherapy; dysphagia; edema; epiglottis; female; fluoroscopy; hospital; human; incidence; major clinical study; male; mucosa; nasopharynx; nasopharynx carcinoma; questionnaire; soft tissue; swallowing; symptom; videorecording; Adult; Deglutition; Deglutition Disorders; Female; Hospitals, University; Humans; Incidence; Male; Middle Aged; Nasopharyngeal Neoplasms; Prospective Studies; Radiation Injuries |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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