https://scholars.lib.ntu.edu.tw/handle/123456789/556790
標題: | Relapse of imported vivax malaria despite standard-dose primaquine therapy: An investigation with molecular genotyping analyses | 作者: | Chiang T.-Y. Lin W.-C. Kuo M.-C. Ji D.-D. CHI-TAI FANG |
公開日期: | 2012 | 出版社: | Blackwell Publishing Ltd | 卷: | 18 | 期: | 7 | 起(迄)頁: | E232-E234 | 來源出版物: | Clinical Microbiology and Infection | 摘要: | Taiwan CDC investigated four cases of recurrent imported vivax malaria during 2003-2010. Molecular genotyping results and the lack of inter-episodes travel history indicated that two of the patients, who acquired vivax malaria in Indonesia and the Solomon Islands, respectively, suffered relapses after an interval of 3-4months, despite completing standard-dose primaquine therapy (30mg/day for 14days) for the first episode. Treatment with a higher dose of primaquine (60mg/day for 14days) prevented further relapse in both patients. This finding calls for further monitoring of the therapeutic efficacy of primaquine in treating Plasmodium vivax acquired in southeast Asia and Oceania. ? 2012 The Authors. Clinical Microbiology and Infection ? 2012 European Society of Clinical Microbiology and Infectious Diseases. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84862618379&doi=10.1111%2fj.1469-0691.2012.03820.x&partnerID=40&md5=9775769b58d1ce781204ce3f3c17d649 https://scholars.lib.ntu.edu.tw/handle/123456789/556790 |
ISSN: | 1198-743X | DOI: | 10.1111/j.1469-0691.2012.03820.x | SDG/關鍵字: | primaquine; adult; article; case report; drug efficacy; drug megadose; female; genetic analysis; human; Indonesia; malaria control; male; molecular genetics; Pacific islands; Plasmodium vivax malaria; priority journal; relapse; Solomon Islands; Southeast Asia; Taiwan; Plasmodium vivax |
顯示於: | 流行病學與預防醫學研究所 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。