https://scholars.lib.ntu.edu.tw/handle/123456789/556870
標題: | Life-threatening scrub typhus with meningoencephalitis and acute respiratory distress syndrome | 作者: | CHI-TAI FANG Ferng W.-F. HWANG, JUEY-JEN CHONG-JEN YU YEE-CHUN CHEN Wang M.-H. SHAN-CHWEN CHANG Hsieh W.-C. |
公開日期: | 1997 | 卷: | 96 | 期: | 3 | 起(迄)頁: | 213-216 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | A 21-year-old man presented with fever, rash, seizure, stiff neck and rapidly progressive bilateral pulmonary infiltrates. Cerebrospinal fluid (CSF) study revealed pleocytosis with predominant polymorphonuclear cells, and hypo-glycorrhachia. Status epilepticus occurred, followed by acute respiratory distress syndrome with respiratory failure. Blood and CSF cultures for bacteria were negative, but an indirect immunofluorescence assay revealed a fourfold rise in antibody to Rickettsia tsutsugamushi in paried serum and a 1:2560 (+) IgM antibody titer. Severe scrub typhus with meningoencephalitis and extensive pneumonitis was diagnosed. The patient survived after intravenous minocycline therapy and intensive care, including aggressive seizure control, supportive mechanical ventilation and avoidance of fluid overloading. He had a nearly complete recovery. Practicing physicians in Taiwan should be aware of this reportable disease and its potentially serious complications if not promptly diagnosed and treated. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0030975583&partnerID=40&md5=2c2d184968445a24d2a876ee658f2cec https://scholars.lib.ntu.edu.tw/handle/123456789/556870 |
ISSN: | 0929-6646 | SDG/關鍵字: | ceftriaxone; minocycline; phenobarbital; adult; adult respiratory distress syndrome; article; artificial ventilation; case report; fever; human; intensive care; intravenous drug administration; male; meningoencephalitis; Orientia tsutsugamushi; pneumonia; rash; scrub typhus; seizure; serodiagnosis; Taiwan; Adult; Humans; Male; Meningoencephalitis; Respiratory Distress Syndrome, Adult; Scrub Typhus |
顯示於: | 流行病學與預防醫學研究所 |
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