Editor's Note: MicroRNA-519c Suppresses Hypoxia-Inducible Factor-1α Expression and Tumor Angiogenesis
Journal
Cancer research
Journal Volume
79
Journal Issue
14
Date Issued
2019-07-15
Author(s)
Cha, Shih-Ting
Chen, Pai-Sheng
Johansson, Gunnar
Wang, Ming-Yang
Jee, Shiou-Hwa
Kuo, Min-Liang
Abstract
The editors were made aware of concerns by a reader regarding potential manipulation of data in this article (1). An internal review by the editors determined that the same RT-PCR bands appear to be duplicated in the A549/HIF-1a and MDA-MB-231/GAPDH panels in Fig. 1B. In addition, it appears that the same Western blot image was used in Fig. 2A (HIF-1b) and Fig. 3D (Actin/Met inhibitor), and that the Akt and Actin Western blot images in Fig. 3A are identical. Because satisfactorily corrected figures could not be provided, the editors are publishing this note to alert readers to these concerns.
SDGs
Type
journal article