Water extract of Armillaria mellea (Vahl) P. Kumm. Alleviates the depression-like behaviors in acute- and chronic mild stress-induced rodent models via anti-inflammatory action
Journal
Journal of Ethnopharmacology
Journal Volume
265
Date Issued
2021-01-30
Author(s)
Lin, Yu-En
Wang, Hsiang-Lan
Huang, Yun-Ju
Panyod, Suraphan
Liu, Wei-Ting
Yang, Shu-Hui
Chen, Mei-Hsing
Lu, Yun-Shen
Abstract
Armillaria mellea (Vahl) P. Kumm. (AM) is an edible mushroom that has been reported as treatment for several neurological disorders, such as dizziness and epilepsy in Asia. Importantly, AM shares a symbiotic relationship with Gastrodia elata Blume (GE), a medicinal herb with antidepressant-like properties. Researchers believe that AM may possess pharmacological properties similar to GE due to their symbiosis, however, few studies have investigated the pharmacological effect of AM.
Subjects
Armillaria mellea (Vahl) P. Kumm.; Depression; Inflammation; Microglia; Unpredictable chronic mild stress
Type
journal article