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  4. Is old age a contraindication for surgical treatment in acute aortic dissection? A demographic study of national database registry in Taiwan
 
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Is old age a contraindication for surgical treatment in acute aortic dissection? A demographic study of national database registry in Taiwan

Journal
Journal of Cardiac Surgery
Journal Volume
23
Journal Issue
2
Pages
133-139
Date Issued
2008
Author(s)
I-HUI WU  
HSI-YU YU  
Liu C.-H.
YIH-SHARNG CHEN  
SHOEI-SHEN WANG  
Lin F.-Y.
DOI
10.1111/j.1540-8191.2007.00565.x
URI
https://www.scopus.com/inward/record.uri?eid=2-s2.0-39849092409&doi=10.1111%2fj.1540-8191.2007.00565.x&partnerID=40&md5=d4f97b2d68f41fbdf7221413543771b2
https://scholars.lib.ntu.edu.tw/handle/123456789/559935
Abstract
Background: Acute aortic dissection is usually presented as a surgical emergent condition with high mortality rate. Whether any patient of an advanced age suffering from acute aortic type A dissection or complicated type B dissection should be referred for surgery still deserves debating. Materials and Methods: A retrospective study including 5654 patients with acute aortic dissection was collected from the National Health Insurance Databases from 1996 to 2001. Age, initial treatment modality, and the late outcome were the main factors to be investigated. Patients are grouped into the young age group when ages are less or equal to 70 and the old age group when over 70. We further subdivided both groups into operative and nonoperative subgroups, respectively, depending on patients receiving surgical intervention for acute aortic dissection or not. The endpoint mortality was defined by the patient death either related to or unrelated to cardiac causes. Results: A total of 5654 cases are with the mean age of 65.6 ± 14.0 years. The percentage of patients receiving operation was inversely related to the patient's age significantly (p < 0.05). In the old age group, the operative subgroup had both significantly higher survival rate at six-year follow-up than the nonoperative group for both patients on admission and 30-day survivors (43.4 ± 3.5% vs. 29.8 ± 2.3%, p < 0.05; 70.0 ± 4.5% vs. 36.0 ± 2.8%, p < 0.05). The annual attrition rates of mortality were significantly higher in the nonoperative subgroup for both patients on admission and 30-day survivors (p < 0.05). Conclusion: The trend toward more conservative treatment in the elderly still occurs in our common practice even with improving surgical techniques. In our study, we suggest that pertinent surgical strategies for acute aortic dissection are necessary to improve the outcome in elderly patients. ? 2008 by Blackwell Futura Publishing, Inc.
SDGs

[SDGs]SDG3

Other Subjects
adult; aged; aorta dissection; article; controlled study; female; human; major clinical study; male; patient care; senescence; surgical technique; survival rate; thoracic aorta surgery; treatment contraindication; treatment outcome; Acute Disease; Adult; Age Factors; Aged; Aged, 80 and over; Aneurysm, Dissecting; Aortic Aneurysm, Thoracic; Decision Making; Female; Geriatric Assessment; Humans; Insurance, Health; Male; Middle Aged; Postoperative Period; Registries; Retrospective Studies; Survival Analysis; Taiwan; Time Factors; Treatment Outcome
Type
journal article

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