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  4. Mitral tetrahedron as a geometrical surrogate for chronic ischemic mitral regurgitation
 
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Mitral tetrahedron as a geometrical surrogate for chronic ischemic mitral regurgitation

Journal
American Journal of Physiology - Heart and Circulatory Physiology
Journal Volume
289
Journal Issue
3 58-3
Pages
H1218-H1225
Date Issued
2005
Author(s)
HSI-YU YU  
MAO-YUAN SU  
YIH-SHARNG CHEN  
Lin F.-Y.
WEN-YIH TSENG  
DOI
10.1152/ajpheart.00169.2005
URI
https://www.scopus.com/inward/record.uri?eid=2-s2.0-23944490636&doi=10.1152%2fajpheart.00169.2005&partnerID=40&md5=c45d076dbdc7f8cd9946acab13188fd4
https://scholars.lib.ntu.edu.tw/handle/123456789/559960
Abstract
The present study tests the hypothesis that a mitral tetrahedron (MT) is a useful geometrical surrogate for assessment of chronic ischemic mitral regurgitation (CIMR). Fifty-eight subjects were divided into three groups on the basis of left ventricular ejection fraction (LVEF) and the presence or absence of CIMR: LVEF ?0.5 and negative CIMR (group 1, n = 28), LVEF <0.5 and negative CIMR (group 2, n = 12), and LVEF <0.5 and positive CIMR (group 3, n = 18). MT was defined by its four vertices at the anterior annulus, posterior annulus, and medial and lateral papillary muscle roots, determined by MRI at peak systole. The results showed no clear cutoff values of MT parameters between groups 2 and 1. In contrast, all MT indexes were significantly different between groups 3 and 2 (P < 0.05), and significant cutoff values differentiated the two groups. A scoring system employing parameters of the whole MT confirmed the absence of CIMR with total edge length index <268 mm/BSA1/3, total surface area index <2,528 mm2/BSA 2/3, and volume index <5,089 mm3/BSA (where BSA is body surface area). The sensitivity, specificity, and positive and negative predictive values were 1.00. This preliminary study demonstrates that MT might serve as a good geometrical surrogate for assessing CIMR. The derived geometrical criteria of MT may be useful in surgical correction of CIMR. Copyright ? 2005 the American Physiological Society.
SDGs

[SDGs]SDG3

Other Subjects
adult; angiocardiography; article; body surface; coronary artery disease; female; geometry; heart left ventricle ejection fraction; heart papillary muscle; human; major clinical study; male; mitral valve regurgitation; nuclear magnetic resonance imaging; priority journal; scoring system; sensitivity and specificity; systole; Adult; Aged; Chronic Disease; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Mitral Valve; Mitral Valve Insufficiency; Myocardial Ischemia; Severity of Illness Index
Type
journal article

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