Heart retransplantation for pediatric primary allograft failure
Journal
Transplantation Proceedings
Journal Volume
44
Journal Issue
4
Pages
913
Date Issued
2012-05
Author(s)
Luo J.M.
Ko W.J.
Abstract
Purpose: Heart transplantation is indicated for children with end-stage heart failure or complex inoperable congenital defects. When the transplanted heart fails, retransplantation is suggested and herein we have presented the prognosis of these pediatric cases. Materials and methods: From March 1987 to March 2011, we performed 404 heart transplantations including 45 pediatric patients, 6 (13.3%) of whom experienced graft failure requiring retransplantation. Only four of the six patients (66.7%) had a chance for retransplantation. Results: Six of 45 pediatric heart transplant patients (13.3%) experienced graft failure requiring retransplantation. Four of them (66.7%) underwent retransplantation. Only one of the four died due to severe postoperative sepsis with acute respiratory distress. The other three patients recovered well and remain alive with no neurological sequelae; all are in New York Heart Association functional classification I at present. Conclusion: Pediatric post-heart graft failure require expectations retransplantation, which shows a good prognosis. ? 2012 Elsevier Inc.
SDGs
Other Subjects
azathioprine; cyclosporin; mycophenolic acid; steroid; cardiac allograft vasculopathy; cardiac graft rejection; child; clinical article; conference paper; female; graft failure; heart transplantation; human; male; outcome assessment; pediatric cardiology; postoperative period; priority journal; prognosis; respiratory distress; retransplantation; sepsis; treatment indication; treatment outcome; Adolescent; Cardiomyopathy, Dilated; Child; Child, Preschool; Coronary Artery Disease; Heart Transplantation; Humans; Male; Reoperation; Respiration Disorders; Sepsis; Taiwan; Time Factors; Transposition of Great Vessels; Treatment Failure
Type
conference paper