Status for clinically complete remission rectal cancer after concomitant chemo-radiotherapy in Taiwan
Journal
Asian Journal of Surgery
Journal Volume
41
Journal Issue
3
Pages
203-209
Date Issued
2018
Author(s)
Abstract
Treatment for Rectal cancer changed after the induction of concomitant chemo-radiotherapy, CCRT. Complete remission of the tumor leads to debate of the necessity of surgical intervention. We evaluate the treatment outcome to know if operation is beneficial to these patients. Patients received long course concomitant chemo-radiotherapy for advanced rectal cancer between 2004 and 2013 in Taiwan were enrolled. Total 2780 patients diagnosed advanced rectal cancer were enrolled. In these patients, 2578 received surgical intervention and 202 were in wait and see for complete remission tumor. Higher local recurrence rate was found with wait and see group (8.9% vs. 2.7%). Also, better overall survival, disease free survival and local recurrence free survival were seen with the surgical intervention group. Surgical intervention may be benefit for some misdiagnosed completed response to CCRT. ? 2017
SDGs
Other Subjects
adjuvant chemoradiotherapy; adult; aged; epidemiology; etiology; female; follow up; human; male; middle aged; mortality; neoadjuvant therapy; prevention and control; rectum; rectum tumor; retrospective study; surgery; survival analysis; Taiwan; treatment outcome; tumor recurrence; very elderly; Adult; Aged; Aged, 80 and over; Chemoradiotherapy, Adjuvant; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Rectal Neoplasms; Rectum; Retrospective Studies; Survival Analysis; Taiwan; Treatment Outcome
Publisher
Elsevier (Singapore) Pte Ltd
Type
review