https://scholars.lib.ntu.edu.tw/handle/123456789/560799
標題: | Risk of Skin Cancer among Patients with Chronic Kidney Disease Treated with Ultraviolet B Phototherapy for Uraemic Pruritus: A Nationwide Cohort Study | 作者: | Ko, Mei-Ju JENQ-WEN HUANG Wu, Hon-Yen Tsai, Wan-Chuan Hsu, Le-Yin Tsai, Ping-Hsiu KUO-LIONG CHIEN KUAN-YU HUNG |
關鍵字: | chronic kidney disease; skin cancer; uraemic pruritus; UVB phototherapy;Chronic kidney disease; Skin cancer; Uraemic pruritus; UVB phototherapy | 公開日期: | 11-二月-2021 | 卷: | 101 | 期: | 2 | 來源出版物: | Acta dermato-venereologica | 摘要: | The safety of ultraviolet B (UVB) phototherapy with respect to cutaneous carcinogenesis has not been established for patients with chronic kidney disease. To investigate this issue, a nationwide cohort study of 10,805 patients with advanced chronic kidney disease was conducted using data from the National Health Insurance of Taiwan, the Taiwan Cancer Registry, and the national death registry. After a median follow-up of 75 months, 16 of 2,161 patients in the UVB group and 63 of 8,644 patients in the non-UVB group developed skin cancers. Compared with the non-UVB group, patients in the UVB group did not show an increased risk of skin cancer (hazard ratio 1.066; 95% confidence interval 0.584-1.944), non-melanoma skin cancer (hazard ratio 1.067; 95% confidence interval 0.571-1.996), or cutaneous melanoma (hazard ratio 1.009; 95% confidence interval 0.115-8.879). In addition, patients who received more UVB phototherapy did not show an increased risk of skin cancer. UVB phototherapy appears to be a safe treatment for uraemic pruritus in patients with chronic kidney disease. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/560799 | ISSN: | 00015555 | DOI: | 10.2340/00015555-3758 | SDG/關鍵字: | hydrochlorothiazide; immunosuppressive agent; adult; Article; cancer registry; cancer risk; chronic kidney failure; cohort analysis; confidence interval; controlled study; cutaneous melanoma; data analysis software; death registry; disease risk assessment; drug use; female; follow up; hazard ratio; human; kidney transplantation; major clinical study; male; middle aged; national health insurance; non melanoma skin cancer; phototherapy; priority journal; proportional hazards model; renal replacement therapy; skin cancer; skin carcinogenesis; skin pruritus; Taiwan; ultraviolet B radiation; ultraviolet phototherapy; uremia; adverse event; chronic kidney failure; melanoma; phototherapy; pruritus; skin tumor; Cohort Studies; Humans; Melanoma; Phototherapy; Pruritus; Renal Insufficiency, Chronic; Skin Neoplasms; Taiwan; Ultraviolet Therapy |
顯示於: | 醫學系 |
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