Bacteraemia caused by non-freundii, non-koseri Citrobacter species in Taiwan
Journal
Journal of Hospital Infection
Journal Volume
76
Journal Issue
4
Pages
332-335
Date Issued
2010
Author(s)
Abstract
This study analysed the clinical characteristics of bacteraemia due to unusual Citrobacter species. All non-freundii and non-koseri Citrobacter isolates were identified to species level by two commercial identification methods and 16S rRNA gene sequence analysis. A total of 306 patients with Citrobacter spp. bacteraemia were identified from January 2000 through December 2009. Four patients (1.3%) had C. braakii bacteraemia, and one had C. amalonaticus and C. sedlakii sepsis, respectively. Misidentification as non-freundii and non-koseri Citrobacter spp., which occurred in eight isolates with the Phoenix automated system PMIC/ID-30 and three with the Vitek II system, occurred in five of six infection episodes. Among the six patients with bacteraemia caused by non-freundii and non-koseri Citrobacter spp., five (83.3%) had healthcare-associated infection and five (83.3%) infections were secondary to intra-abdominal infection. Cancer and liver cirrhosis were the commonest underlying diseases. An attributable mortality was 33.3%. Antimicrobial susceptibility testing showed that the resistance patterns varied among different Citrobacter species. Non-freundii and non-koseri Citrobacter species are difficult to identify and are a rare cause of intra-abdominal infections with secondary healthcare-associated bacteraemia in immunocompromised patients. ? 2010 The Hospital Infection Society.
SDGs
Other Subjects
aminoglycoside antibiotic agent; cefepime; ciprofloxacin; imipenem; antibiotic sensitivity; article; bacteremia; bacterium identification; Citrobacter; citrobacter amalonaticus; Citrobacter amalonaticus infection; Citrobacter braakii; Citrobacter braakii infection; Citrobacter sedlakii; Citrobacter sedlakii infection; healthcare associated infection; human; infection; nonhuman; nucleotide sequence; Taiwan; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Bacterial Typing Techniques; Citrobacter; DNA, Bacterial; DNA, Ribosomal; Enterobacteriaceae Infections; Female; Humans; Male; Microbial Sensitivity Tests; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Taiwan
Type
journal article