https://scholars.lib.ntu.edu.tw/handle/123456789/561166
標題: | Invasive infections caused by non-Aspergillus moulds identified by sequencing analysis at a tertiary care hospital in Taiwan, 2000-2008 | 作者: | Hsiue H.-C. SHENG-YUAN RUAN Kuo Y.-L. YU-TSUNG HUANG PO-REN HSUEH |
公開日期: | 2010 | 卷: | 16 | 期: | 8 | 起(迄)頁: | 1204-1206 | 來源出版物: | Clinical Microbiology and Infection | 摘要: | The clinical and microbiological characteristics of 103 patients with cultures positive for non-Aspergillus moulds in the period 2000 to 2008 were described. Among these patients, 27 had proven or probable invasive infections caused by Fusarium (n = 12), Paecilomyces (n = 7), Zygomycetes (n = 5) and Scedopsorium species (n = 3). The incidence of invasive infections caused by these moulds has not increased during the study period. Lung was the most common infection site and disseminated disease was observed in three leukaemic patients. The overall mortality rate was 40.7%, and was highest in cases zygomycosis. Antifungal susceptibility varied considerably among species. Amphotericin B and posaconazole demonstrated greatest activity against these moulds. ? 2010 The Authors. Journal Compilation ? 2010 European Society of Clinical Microbiology and Infectious Diseases. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/561166 | ISSN: | 1198-743X | DOI: | 10.1111/j.1469-0691.2009.03103.x | SDG/關鍵字: | amphotericin B; anidulafungin; caspofungin; elongation factor 1; elongation factor 1alpha; elongation factor 2; fluconazole; internal transcribed spacer; internal transcribed spacer 1; internal transcribed spacer 4; itraconazole; micafungin; posaconazole; unclassified drug; voriconazole; amphotericin B; antifungal agent; adolescent; adult; aged; antifungal susceptibility; article; Aspergillus; child; controlled study; female; fungal detection; fungus culture; fungus isolation; Fusarium; human; immunocompromised patient; infant; leukemia; lung mycosis; major clinical study; male; minimum inhibitory concentration; mortality; mould; nonhuman; Paecilomyces; preschool child; priority journal; school child; sequence analysis; species comparison; systemic mycosis; Taiwan; Zygomycetes; zygomycosis; classification; DNA sequence; fungus; genetics; hospital; incidence; isolation and purification; microbial sensitivity test; middle aged; mycology; Mycoses; newborn; procedures; very elderly; young adult; Adolescent; Adult; Aged; Aged, 80 and over; Amphotericin B; Antifungal Agents; Child; Child, Preschool; Female; Fungi; Hospitals; Humans; Incidence; Infant; Infant, Newborn; Male; Microbial Sensitivity Tests; Middle Aged; Mycology; Mycoses; Sequence Analysis, DNA; Taiwan; Young Adult |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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