https://scholars.lib.ntu.edu.tw/handle/123456789/561911
標題: | Descending necrotizing mediastinitis: A 10-year surgical experience in a single institution | 作者: | KE-CHENG CHEN JIN-SHING CHEN SHUENN-WEN KUO PEI-MING HUANG HSAO-HSUN HSU JANG-MING LEE Lee, Yung-Chie |
公開日期: | 2008 | 卷: | 136 | 期: | 1 | 起(迄)頁: | 191-198 | 來源出版物: | Journal of Thoracic and Cardiovascular Surgery | 摘要: | Objective: Early diagnosis and aggressive surgical drainage are very important for successful treatment of descending necrotizing mediastinitis. However, the surgical techniques used for this condition remain controversial. We report our 10-year experience of managing this devastating disease, focusing on the multidisciplinary, minimally invasive operative procedures and the unique bacteriologic factors in Taiwan. Methods: Between January 1997 and January 2007, we retrospectively reviewed 18 patients with descending necrotizing mediastinitis who were treated in the National Taiwan University Hospital. Diagnosis and Endo classification were confirmed by computed tomography of the neck and chest. Results: Eight women and 10 men were included in this study. The mean age was 57.8 ± 15.2 years. Cervical drainage was performed in the involved area in all patients. The methods for mediastinal drainage included transcervical (n = 10), video-assisted thoracic surgical drainage (n = 6), subxiphoid drainage (n = 1), and mediastinoscopy-assisted drainage (n = 1). We could not rescue 3 patients because of uncontrolled sepsis before surgery, for a mortality rate of 16.7%. Klebsiella pneumoniae uniquely represents the most common pathogen in diabetic patients (P = .01), leading to more complicated courses in older patients (P =.04) and requiring more surgical interventions (P =.05) than other pathogens. Conclusion: Transcervical mediastinal drainage is first justified in patients with limited disease in the upper mediastinum. For those with involvement of the lower anterior mediastinum, an additional subxiphoid approach is suggested. Cervicotomy with video-assissted mediastinal drainage is an excellent combination for involvement of the posterior mediastinum and pleural space. Klebsiella pneumoniae uniquely represents the most important and threatening causative pathogen for diabetic patients with descending necrotizing mediastinitis. ? 2008 The American Association for Thoracic Surgery. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-46049111409&doi=10.1016%2fj.jtcvs.2008.01.009&partnerID=40&md5=0069e3a273635c749b34e36b1ff0e73c https://scholars.lib.ntu.edu.tw/handle/123456789/561911 |
ISSN: | 0022-5223 | DOI: | 10.1016/j.jtcvs.2008.01.009 | SDG/關鍵字: | adolescent; adult; aged; article; bacteriology; clinical article; computer assisted tomography; diabetic patient; early diagnosis; female; human; Klebsiella pneumoniae; male; mediastinitis; mediastinoscopy; minimally invasive surgery; mortality; priority journal; retrospective study; sepsis; surgical drainage; Taiwan; treatment outcome; Abscess; Adult; Aged; Causality; Comorbidity; Coronary Artery Disease; Debridement; Diabetes Mellitus; Drainage; Female; Foreign Bodies; Humans; Hypertension; Liver Cirrhosis; Male; Mediastinitis; Mediastinum; Middle Aged; Pleura; Retrospective Studies; Taiwan; Thoracic Surgery, Video-Assisted; Tomography, X-Ray Computed; Treatment Outcome |
顯示於: | 醫學系 |
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