https://scholars.lib.ntu.edu.tw/handle/123456789/563742
標題: | Incidental solitary knee mass as the first manifestation of hidden lung cancer | 作者: | Hsieh C.-C. RONG-SEN YANG Huang K.-Y. |
公開日期: | 2009 | 卷: | 16 | 期: | 2 | 起(迄)頁: | 161-164 | 來源出版物: | Knee | 摘要: | Hypertrophic pulmonary osteoarthropathy (HPOA), also known as secondary hypertrophic osteoarthropathy, is a clinical syndrome characterized by proliferative periostitis of the long bones especially in the distal and periarticular aspects, proliferation of the synovial membranes, causing painful and swollen joints, and often with finger clubbing. It is associated with various underlying causes, including pulmonary, pleural, cardiac, abdominal and miscellaneous conditions. Its pulmonary causes include bronchogenic carcinoma, tuberculosis, pulmonary abscess, bronchiectasis, emphysema, etc. Its radiographic presentation involves periostitis in the lower extremities. We report one case that had an incidental finding of HPOA with initial complaint about an incidental solitary knee mass with painful swelling of right knee, leading to early diagnosis of occult bronchogenic carcinoma. The radiographs and magnetic resonance imaging (MRI) revealed periosteal reactions without definite intraosseous lesion. Chest radiography and CT scan disclosed an infiltrating right upper lobe lesion suspicious malignancy. Patient received right S2 segmentectomy of lung with pathological confirmation of adenocarcinoma of lung cancer. It is important for the clinician to be aware of the radiographic findings of periostitis of HPOA, which may be the clues leading to early detection of lung cancer without significant pulmonary symptoms and to avoid possible tumor progression and distant metastases. ? 2008 Elsevier B.V. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-58649086502&doi=10.1016%2fj.knee.2008.10.001&partnerID=40&md5=6260994d56d094c1921c76e9e2980536 https://scholars.lib.ntu.edu.tw/handle/123456789/563742 |
ISSN: | 0968-0160 | DOI: | 10.1016/j.knee.2008.10.001 | SDG/關鍵字: | alpha fetoprotein; carcinoembryonic antigen; prostate specific antigen; tissue polypeptide antigen; adult; article; bone radiography; cancer diagnosis; cancer growth; case report; computer assisted tomography; distant metastasis; early diagnosis; histopathology; human; human tissue; incidental finding; knee pain; lung adenocarcinoma; lung lobe; male; nuclear magnetic resonance imaging; osteoarthropathy; periosteum; periostitis; priority journal; smoking; swelling; thorax radiography; Carcinoma, Bronchogenic; Humans; Incidental Findings; Knee; Lung Neoplasms; Male; Middle Aged; Osteoarthropathy, Secondary Hypertrophic; Smoking |
顯示於: | 醫學系 |
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