https://scholars.lib.ntu.edu.tw/handle/123456789/565749
標題: | Diagnostic role of endoscopy, stool culture, and toxin A in Clostridium difficile-associated disease | 作者: | SHU-CHEN WEI Wong J.-M. PO-REN HSUEH MING-JIUM SHIEH Wang T.-H. KWEN-TAY LUH Wang C.-Y. |
公開日期: | 1997 | 卷: | 96 | 期: | 11 | 起(迄)頁: | 879-883 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | This retrospective study was designed to asses the roles of stool culture for Clostridium difficile, detection of the presence of toxin A, and endoscopic examination in the diagnosis of Clostridium difficile-associated disease (CDAD). From January 1994 through September 1996, there were 213 patients with stool cultures positive for C. difficile in National Taiwan University Hospital. Of these, 126 had CDAD. There were 87 asymptomatic carriers of C. difficile in our study, 12 of whom were positive for toxin A. In addition, seven patients with pseudomembranous colitis (PMC), who were either culture-negative or not tested, were included in the study. The positive predictive values of stool cultures for CDAD and PMC were 59% and 32%, respectively. The positive predictive values of toxin A for CDAD and PMC were 41% and 43%, respectively. Seventy-eight patients (59%) improved with supportive treatment after discontinuing antibiotics. We concluded that stool culture for C. difficile and discontinuation of antibiotics should be the standard approach for patients with suspected CDAD. Endoscopic studies can eliminate some other possible causes of diarrhea such as inflammatory bowel disease, allow biopsies of suspicious lesions, and reveal the severity of CDAD. Toxin assay results need to be interpreted together with the clinical data. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031413867&partnerID=40&md5=bf6dfe2242390d27d7584c848eee76d9 https://scholars.lib.ntu.edu.tw/handle/123456789/565749 |
ISSN: | 0929-6646 | SDG/關鍵字: | article; bacterial infection; clinical feature; clostridium difficile; diagnostic value; endoscopy; feces culture; Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Toxins; Child; Child, Preschool; Endoscopy, Gastrointestinal; Enterocolitis, Pseudomembranous; Enterotoxins; Feces; Female; Humans; Infant; Male; Middle Aged; Retrospective Studies |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。