Biosynthesis of superoxide dismutase in Sacchromyces cerevisiae: Effects of paraquat and copper
Journal
Journal of Free Radicals in Biology and Medicine
Journal Volume
1
Journal Issue
4
Pages
319-325
Date Issued
1985
Author(s)
Hassan H.M.
Abstract
Growth of Saccharomyces cerevisiae in the presence of paraquat caused an increase the intracellular flux of superoxide radicals and in superoxide dismutase biosynthesis. The addition of copper to the growth medium also elicited an increase in superoxide dismutase levels. A cytochrome c deficient mutant strain was found to be more responsive than the wild type strain to paraquat and/or copper by increasing its copper-zinc superoxide dismutase. Catalase activity in both strains was not significantly affected by paraquat and/or copper.
Type
journal article