https://scholars.lib.ntu.edu.tw/handle/123456789/568576
標題: | Hospital-based surveillance and molecular epidemiology of rotavirus infection in Taiwan, 2005-2007 | 作者: | Wu F.T. Liang S.Y. Tsao K.C. Huang C.G. Lin C.Y. Lin J.S. Su C.Y. Eng H.L. Yang J.Y. PEI-JER CHEN Yang C.F. |
關鍵字: | Rotavirus diarrhoea; Seasonality distribution; Strain genotyping | 公開日期: | 2009 | 卷: | 27 | 期: | SUPPL. 5 | 起(迄)頁: | F50-F54 | 來源出版物: | Vaccine | 摘要: | To determine the distribution of rotavirus strains and facilitate vaccine policy decisions in Taiwan, active hospital-based gastroenteritis surveillance was conducted in three sentinel hospitals. From 1 January 2005 to 31 December 2007, a total of 3435 children less than 5 years old with gastroenteritis were enrolled. The presence of rotavirus was documented by enzyme immunoassay (EIA), and the G and P genotypes were determined by reverse transcription-polymerase chain reaction (RT-PCR) and sequencing methods. Results confirmed that 856 (25%) of these gastroenteritis admissions were EIA-positive for rotavirus and 448 (52%) of the rotavirus positive admissions were less than 2 years old. The most prevalent rotavirus genotypes were G1P[8] (40%), followed by strains G3P[8] (27%), and G9P[8] (17%). These data will help inform decisions as to whether rotavirus vaccine should be considered for inclusion into Taiwan's National Immunisation Programme. ? 2009 Elsevier Ltd. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-71649098267&doi=10.1016%2fj.vaccine.2009.08.090&partnerID=40&md5=3eafb22e2044124a9008c114d7ef7c2f https://scholars.lib.ntu.edu.tw/handle/123456789/568576 |
ISSN: | 0264-410X | DOI: | 10.1016/j.vaccine.2009.08.090 | SDG/關鍵字: | article; child; child hospitalization; disease surveillance; female; gastroenteritis; genotype; human; infant; major clinical study; male; molecular epidemiology; nonhuman; preschool child; prevalence; priority journal; Rotavirus; seasonal variation; Taiwan; virus detection; virus infection; virus strain; Age Distribution; Child, Preschool; Diarrhea; Female; Gastroenteritis; Genotype; Hospitals; Humans; Infant; Male; Molecular Epidemiology; Prevalence; Rotavirus; Rotavirus Infections; Seasons; Sentinel Surveillance; Taiwan |
顯示於: | 臨床醫學研究所 |
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