https://scholars.lib.ntu.edu.tw/handle/123456789/568777
標題: | Prevalence and implication of a newly identified infectious agent (SEN virus) in Taiwan | 作者: | JIA-HORNG KAO Chen W. PEI-JER CHEN Lai M.-Y. DING-SHINN CHEN |
公開日期: | 2002 | 卷: | 185 | 期: | 3 | 起(迄)頁: | 389-392 | 來源出版物: | Journal of Infectious Diseases | 摘要: | To investigate the prevalence and clinical relevance of a recently identified SEN virus (SENV) in Taiwan, 2 SENV variants (SENV-D and SENV-H) were studied in high-risk persons, patients with liver disease, and healthy adults. SENV-D and/or SENV-H (SENV-D/H) infections were more frequent in high-risk groups (54%-90%) and in patients with chronic hepatitis B (41%), hepatitis B-related hepatocellular carcinoma (HCC) (54%), chronic hepatitis C (67%), and hepatitis C-related HCC (76%) than in healthy adults (15%). The prevalence of SENV-D/H infection was comparable between patients with non-A to E fulminant hepatitis (30%) and healthy adults. Most subjects with SENV-D/H infection alone had no or mild hepatitis, and coinfection of SENV-D/H with chronic hepatitis B or C was not associated with increased evidence of liver disease and the risk of HCC. These results suggest that SENV-D/H infection is common in high-risk groups in Taiwan but that SENV-D/H infection is not associated with hepatitis. ? 2001 Infectious Diseases Society of America. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84984538657&doi=10.1086%2f338472&partnerID=40&md5=a07bb55fabaef970c4b407f2c0d67c4e https://scholars.lib.ntu.edu.tw/handle/123456789/568777 |
ISSN: | 0022-1899 | DOI: | 10.1086/338472 | SDG/關鍵字: | article; chronic hepatitis; comorbidity; controlled study; disease association; gene amplification; hepatitis B; hepatitis C; high risk population; human; infection risk; liver cell carcinoma; major clinical study; prevalence; priority journal; risk assessment; SEN virus; Taiwan; virus strain |
顯示於: | 臨床醫學研究所 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。