https://scholars.lib.ntu.edu.tw/handle/123456789/569970
標題: | Oral manifestations of human immunodeficiency virus-infected patients in Taiwan | 作者: | CHUN-PIN CHIANG Chueh L.-H. SZE-KWAN LIN Chen M.-Y. |
關鍵字: | HIV infection; Oral candidiasis; Oral hairy leukoplakia; Oral lesions | 公開日期: | 1998 | 卷: | 97 | 期: | 9 | 起(迄)頁: | 600-605 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | To understand the characteristic clinical features of human immunodeficiency virus (HIV)-related oral lesions and determine the prevalence of various oral lesions in HIV-infected patients in Taiwan, we conducted a cross-sectional study of 207 HIV-infected patients at the Taipei Municipal Institute for Venereal Disease Control. Overall, 108 (52.2%) patients had at least one oral lesion. The most common oral manifestation of HIV infection among these 207 patients was oral hairy leukoplakia (OHL, 29.5%), followed by candidiasis (12.1%), xerostomia (10.6%), aphthous ulcers (8.7%), and linear gingival erythema (5.8%). Less frequently encountered oral lesions included leukoplakia (1.9%), papilloma (1.4%), necrotizing ulcerative periodontitis (1.0%), Kaposi's sarcoma (1.0%), herpes simplex (0.5%), Burkitt's lymphoma (0.5%), and parotid gland enlargement (0.5%). Thirty-one (15%) patients had multiple oral lesions. Patients with oral candidiasis or multiple oral lesions had significantly lower mean CD4 lymphocyte counts and CD4/CD8 lymphocyte ratios than those without any oral lesions (p < 0.05). Chi-square analysis revealed that patients with CD4 lymphocyte counts below 200 cells/mm3 were more prone to have OHL (p < 0.002), oral candidiasis (p < 0.001) and multiple oral lesions (p < 0.001). Those with CD4/CD8 lymphocyte ratios below 0.4 were more likely to have OHL (p < 0.02), oral candidiasis (p < 0.01) and multiple oral lesions (p < 0.02) than those with higher counts. In conclusion, the occurrence of oral lesions, especially OHL and oral candidiasis, is fairly common in Taiwanese HIV-infected patients. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0031697566&partnerID=40&md5=85e05f751beb0b3b4ae8598ce8aef7d4 https://scholars.lib.ntu.edu.tw/handle/123456789/569970 |
ISSN: | 0929-6646 | SDG/關鍵字: | adult; aged; aphthous ulcer; article; candidiasis; clinical feature; female; human; human immunodeficiency virus infection; kaposi sarcoma; leukoplakia; lymphocyte count; major clinical study; male; papilloma; periodontitis; prevalence; sexually transmitted disease; taiwan; xerostomia; Adolescent; Adult; Aged; Candidiasis, Oral; CD4 Lymphocyte Count; Female; HIV Infections; Humans; Leukoplakia, Hairy; Male; Middle Aged; Mouth Diseases; Xerostomia |
顯示於: | 臨床牙醫學研究所 |
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