https://scholars.lib.ntu.edu.tw/handle/123456789/570277
標題: | Oral manifestations and blood profile inpatients with thalassemia trait | 作者: | YI-PING WANG JULIA YU-FONG CHANG Wu Y.-C. SHIH-JUNG CHENG HSIN-MING CHEN Sun A. |
公開日期: | 2013 | 卷: | 112 | 期: | 12 | 起(迄)頁: | 761-765 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | Background/Purpose: Patients with thalassemia trait (TT) may have anemia. This study evaluated whether TT patients had specific oral manifestations and a particular blood profile compared with normal individuals. Methods: The oral manifestations and mean red blood cell count, corpuscular cell volume, red blood cell distribution width, Mentzer index, and Green and King index as well as blood concentrations of hemoglobin, iron, total iron binding capacity, vitamin B12, folic acid, and homocysteine in 65 TT patients and in 130 age- and sex-matched healthy controls were measured and compared. Results: TT patients had significantly higher frequencies of all oral manifestations than healthy controls (p<0.001 for all), in which burning sensation of oral mucosa (90.8%), lingual varicosity (90.8%), dry mouth (72.3%), atrophic glossitis (32.3%), and numbness of the oral mucosa (30.8%) were the five leading oral manifestations for TT patients. Moreover, TT patients had significantly lower mean hemoglobin level, corpuscular cell volume, Mentzer index, and Green and King index (p<0.001 for all) as well as significantly higher mean red blood cell count and red blood cell distribution width (p<0.001 for both) than healthy controls. However, no significant difference in the mean blood iron, total iron binding capacity, vitamin B12, folic acid, or homocysteine levels was discovered between 65 TT patients and 130 healthy controls. Conclusion: TT patients have specific oral manifestations and a particular blood profile compared to normal individuals. ? 2013. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84890226352&doi=10.1016%2fj.jfma.2013.09.010&partnerID=40&md5=11cd842c5f46d35be2af7fe4a2a68ece https://scholars.lib.ntu.edu.tw/handle/123456789/570277 |
ISSN: | 0929-6646 | DOI: | 10.1016/j.jfma.2013.09.010 | SDG/關鍵字: | cyanocobalamin; folic acid; hemoglobin; homocysteine; iron; cyanocobalamin; folic acid; hemoglobin; homocysteine; iron; adult; aged; article; blood chemistry; burning sensation; cell volume; cellular distribution; erythrocyte count; female; genetic trait; glossitis; hemoglobin blood level; human; iron binding capacity; iron blood level; major clinical study; male; mouth disease; mouth mucosa; thalassemia; thalassemia trait; xerostomia; atrophy; blood; case control study; complication; glossitis; hypesthesia; mean corpuscular volume; metabolism; middle aged; pathology; thalassemia; tongue; Varicose Veins; vascularization; very elderly; xerostomia; young adult; Adult; Aged; Aged, 80 and over; Atrophy; Case-Control Studies; Erythrocyte Count; Erythrocyte Indices; Female; Folic Acid; Glossitis; Hemoglobins; Homocysteine; Humans; Hypesthesia; Iron; Male; Middle Aged; Mouth Mucosa; Thalassemia; Tongue; Varicose Veins; Vitamin B 12; Xerostomia; Young Adult |
顯示於: | 臨床牙醫學研究所 |
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