Preoperative diagnosis and localization of aldosterone-producing adenoma by adrenal venous sampling after administration of metoclopramide
Journal
Journal of the Formosan Medical Association = Taiwan yi zhi
Journal Volume
100
Journal Issue
9
Date Issued
2001-09
Author(s)
Liao T.-S.
Lai M.-K.
Chen S.-T.
Hsieh B.-S.
Abstract
Adrenal venous sampling is the most reliable test to distinguish aldosterone-producing adenoma (APA) from idiopathic hyperaldosteronism (IHA). The diagnostic accuracy can be improved by administration of adrenocorticotropin to minimize pulsatile secretion of aldosterone. Metoclopramide (MCP), a dopamine antagonist, can increase aldosterone secretion promptly without affecting cortisol secretion. This study investigated the diagnostic accuracy of adrenal venous sampling after MCP injection for the preoperative diagnosis and localization of APA.
Subjects
Adrenal venous sampling | Aldosterone-producing adenoma | Metoclopramide | Preoperative diagnosis | Primary aldosteronism
SDGs
Other Subjects
aldosterone; metoclopramide; adenoma; adrenalectomy; adult; aged; aldosterone blood level; article; blood sampling; clinical article; clinical trial; computer assisted tomography; controlled clinical trial; controlled study; diagnostic accuracy; differential diagnosis; female; hormone synthesis; human; idiopathic disease; inferior cava vein; male; preoperative evaluation; primary hyperaldosteronism; prospective study; tumor localization; vein; vein catheterization; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Male; Metoclopramide; Middle Aged
Type
journal article