Characterization of isoquinoline alkaloids from Neolitsea sericea var. aurata by HPLC-SPE-NMR
Journal
Journal of Natural Products
Journal Volume
70
Journal Issue
4
Pages
637-642
Date Issued
2007
Author(s)
Abstract
Application of the HPLC-SPE-NMR technique to identify the alkaloids in an EtOH extract of the leaves of Neolitsea sericea var. aurata led to the characterization of 14 alkaloids while consuming plant material equivalent to 1.1 g. Of these, seven are N-oxides, four of which are new, namely, 9S,17S-pallidine Nα-oxide (6), 1S,2S-reticuline N α-oxide (8), 6R,6aS-boldine Nβ-oxide (9), and 6S,6aS-N-methyllaurotetanine Nα-oxide (13). Their structures were also confirmed by partial synthesis. © 2007 American Chemical Society and American Society of Pharmacognosy.
SDGs
Type
journal article