Annotation resource of tandem repeat-containing secretory proteins in sixty fungi
Journal
Fungal Genetics and Biology
Journal Volume
119
Pages
7-19
Date Issued
2018
Author(s)
Abstract
Fungal secretory proteins that interact with host plants are regarded as effectors. Because fungal effectors rarely contain conserved sequence features, identification and annotation of fungal effectors from predicted secretory proteins are difficult using outward comparison methods such as BLAST or hidden Markov model. In desire of more sequence features to prioritize research interests of fungal secretory proteins, this study developed a pipeline to identify tandem repeat (TR) domain within putative secretory proteins and tested a hypothesis that at least one type of TR domain in non-orthologous secretory proteins has emerged from convergent evolution for plant pathogenicity. There were 2804 types of TR domains and a total of 2925 TR-containing secretory proteins found from 60 fungi. There was no conserved type of TR domain shared only by plant pathogens, indicating functional divergence for different types of TR domain and TR-containing secretory proteins. The annotation resource of putative fungal TR-containing secretory proteins provides new sequence features that will be useful for the community interested in fungal effector biology. ? 2018
Subjects
fungal secretory protein; secretory protein; unclassified drug; fungal protein; proteome; Alternaria alternata; Alternaria brassicicola; annotation resource; Armillaria mellea; Article; Ascochyta rabiei; Aspergillus flavus; Aspergillus nidulans; Aspergillus oryzae; Beauveria bassiana; Blumeria graminis; Botrytis cinerea; Candida albicans; Cercospora zeae maydis; Cochliobolus heterostrophus; Cochliobolus victoriae; Colletotrichum higginsianum; convergent evolution; Cryphonectria parasitica; Cryptococcus neoformans; Diaporthe ampelina; Erysiphe necator; Eutypa lata; fungus; Fusarium graminearum; Fusarium oxysporum; Fusarium verticillioides; Gaeumannomyces graminis; genetic resource; genetic variability; Glomerella graminicola; Hypocrea jecorina; Leptosphaeria maculans; Macrophomina phaseolina; Magnaporthe grisea; Melampsora larici populina; Melampsora lini; Metarhizium robertsii; Mucor circinelloides; Nectria haematococca; Neurospora crassa; nonhuman; Ophiostoma novo ulmi; Parastagonospora nodorum; Passalora fulva; pathogenicity; Penicillium chrysogenum; Penicillium digitatum; Penicillium expansum; Penicillium oxalicum; Phaeomoniella chlamydospora; plant pathogenicity; priority journal; protein domain; Puccinia graminis; Puccinia striiformis; Pyrenophora tritici repentis; Rhizoctonia solani; Rhizophagus irregularis; Rhizopus microsporus; Rhizopus oryzae; Saccharomyces cerevisiae; Sclerotinia sclerotiorum; Septoria musiva; tandem repeat; Taphrina deformans; Ustilago hordei; Ustilago maydis; Venturia inaequalis; Verticillium alfalfae; Verticillium dahliae; Zymoseptoria tritici; fungal genome; fungus; genetics; Markov chain; microbiology; molecular genetics; plant disease; tandem repeat; Fungal Proteins; Fungi; Genome, Fungal; Markov Chains; Molecular Sequence Annotation; Plant Diseases; Proteome; Tandem Repeat Sequences
SDGs
Type
journal article