https://scholars.lib.ntu.edu.tw/handle/123456789/573708
標題: | Magneto-Optical Characteristics of Streptavidin-Coated Fe3O4@Au Core-Shell Nanoparticles for Potential Applications on Biomedical Assays | 作者: | Lin C.-W., Chen J.-M., Lin Y.-J., Chao L.-W., Wei S.-Y., Wu C.-H., Jeng C.-C., Wang L.-M., Chen K.-L. LI-MIN WANG |
公開日期: | 2019 | 卷: | 9 | 期: | 1 | 來源出版物: | Scientific Reports | 摘要: | Recently, gold-coated magnetic nanoparticles have drawn the interest of researchers due to their unique magneto-plasmonic characteristics. Previous research has found that the magneto-optical Faraday effect of gold-coated magnetic nanoparticles can be effectively enhanced because of the surface plasmon resonance of the gold shell. Furthermore, gold-coated magnetic nanoparticles are ideal for biomedical applications because of their high stability and biocompatibility. In this work, we synthesized Fe3O4@Au core-shell nanoparticles and coated streptavidin (STA) on the surface. Streptavidin is a protein which can selectively bind to biotin with a strong affinity. STA is widely used in biotechnology research including enzyme-linked immunosorbent assay (ELISA), time-resolved immunofluorescence (TRFIA), biosensors, and targeted pharmaceuticals. The Faraday magneto-optical characteristics of the biofunctionalized Fe3O4@Au nanoparticles were measured and studied. We showed that the streptavidin-coated Fe3O4@Au nanoparticles still possessed the enhanced magneto-optical Faraday effect. As a result, the possibility of using biofunctionalized Fe3O4@Au nanoparticles for magneto-optical biomedical assays should be explored. ? 2019, The Author(s). |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85074814900&doi=10.1038%2fs41598-019-52773-7&partnerID=40&md5=4a5a863feb4abd24d3b305dfa3315873 https://scholars.lib.ntu.edu.tw/handle/123456789/573708 |
ISSN: | 20452322 | DOI: | 10.1038/s41598-019-52773-7 |
顯示於: | 物理學系 |
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