One-Pot CuI/DBU-Catalyzed Carboxylative Cyclization toward Oxazolidinones Using Recyclable Molecular Sieves as Efficient Promoters for Fixation of CO2in Water Medium
Journal
Journal of Organic Chemistry
Journal Volume
85
Journal Issue
21
Pages
13655-13663
Date Issued
2020
Author(s)
Liu Y.-T
Abstract
An efficient one-pot synthesis of oxazolidinones was developed through CuI/DBU/MS joint system-catalyzed carboxylative cyclization of arylacetylene, arylaldehyde, and arylamine in water medium under a 1 atm carbon dioxide (CO2) atmosphere. The 4 ? molecular sieves (MSs) were added to improve CO2 capture and facilitate carboxylation to give the products in high yields. The CuI/DBU/MS system is robust and highly effective for the reactions with different substrates, and some target products were obtained in an excellent yield of ?96%, with no side products in the final step. ?
Subjects
Carbon dioxide; Carboxylation; Molecular sieves; Sieves; Aryl acetylenes; Arylaldehyde; Different substrates; Joint system; One-pot synthesis; Oxazolidinones; Side products; Water mediums; Cyclization
Type
journal article