1,3-Dithiolanes (Update 2018)
Journal
Science of Synthesis
Journal Volume
2
Pages
389-463
Date Issued
2018
Author(s)
Abstract
For previously published information, see Section 30.3.3.1. Although 1,3-dithiolanes are stable under both basic and acidic conditions, and can resist attack from certain nucleophiles, organometallic reagents, hydrides, and mild oxidizing agents, they can be effectively converted back into carbonyl groups under various mild conditions. Therefore, the use of a 1,3-dithiolane as a protective group for carbonyl functionalities has been extensive. During the last decades, many different kinds of effective catalysts have been developed to convert carbonyl compounds into 1,3-dithiolanes. ? 2018 Georg Thieme Verlag. All rights reserved.
SDGs
Type
review