|Title:||Clinical and pathological characteristics of mycobacterial tenosynovitis and arthritis||Authors:||Hsiao C.-H.
|Issue Date:||2013||Journal Volume:||41||Journal Issue:||2||Start page/Pages:||457-464||Source:||Infection||Abstract:||
Purpose: To investigate the clinical characteristics and pathological features of patients with mycobacterial tenosynovitis and arthritis. Methods: All patients with tenosynovitis and arthritis caused by Mycobacterium tuberculosis (MTB) and nontuberculous mycobacteria (NTM) who were treated at a medical center in Taiwan from 2001 to 2010 were analyzed. Results: Thirty-two patients with mycobacterial tenosynovitis and arthritis were identified. MTB was isolated exclusively from patients with arthritis of large joints (n = 11), while NTM were isolated from patients with arthritis of large joints (n = 4) and from those with tenosynovitis (n = 17). Among patients with tenosynovitis due to NTM, the most commonly found NTM were M. marinum (n = 7), M. intracellulare (n = 5), and M. abscessus (sensu stricto) (n = 2). Six of the seven patients with tenosynovitis due to M. marinum had suffered fishing-related injuries to the hands. All four patients with NTM arthritis had recurrent septic arthritis after surgery. NTM were isolated once from the debrided tissue specimens in three of these patients; the other patient died of systemic infection caused by M. intracellulare and multiple bacterial pathogens. Conclusion: Mycobacterial tenosynovitis should be considered in patients who present with indolent symptoms of chronic tenosynovitis. Complete clinical information, including history of trauma or joint replacement surgery and underlying systemic disease, is helpful in establishing an early diagnosis of the disease. ? 2013 Springer-Verlag Berlin Heidelberg.
|ISSN:||0300-8126||DOI:||10.1007/s15010-013-0403-5||SDG/Keyword:||ciprofloxacin; clarithromycin; ethambutol; isoniazid; minocycline; pyrazinamide; rifampicin; streptomycin; adult; aged; article; atypical Mycobacterium; bacterial arthritis; bacterium isolation; clinical article; clinical feature; female; fishing; hand injury; histopathology; human; human tissue; male; medical history; mycobacterial arthritis; mycobacterial tenosynovitis; mycobacteriosis; Mycobacterium abscessus; Mycobacterium intracellulare; Mycobacterium marinum; Mycobacterium tuberculosis; nonhuman; recurrent infection; Taiwan; tenosynovitis; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Arthritis, Infectious; Female; Foot Bones; Hand Bones; Humans; Male; Middle Aged; Mycobacterium Infections, Nontuberculous; Mycobacterium marinum; Mycobacterium tuberculosis; Recurrence; Synovial Fluid; Taiwan; Tenosynovitis; Young Adult
|Appears in Collections:||醫學系|
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