https://scholars.lib.ntu.edu.tw/handle/123456789/578403
標題: | Affective and cognitive rather than somatic symptoms of depression predict 3-year mortality in patients on chronic hemodialysis | 作者: | HUI-TENG CHENG Ho M.-C. KUAN-YU HUNG |
公開日期: | 2018 | 出版社: | Nature Publishing Group | 卷: | 8 | 期: | 1 | 起(迄)頁: | 5868 | 來源出版物: | Scientific Reports | 摘要: | Depression is more common in many medical conditions than among the general population and is associated with an increased risk of mortality. We aimed to determine whether somatic symptoms of depression were more predictive of mortality than affective and cognitive symptoms in hemodialysis patients. We conducted a prospective cohort study in which the survival outcomes of 151 subjects were followed for more than 3 years. Depression was assessed with the Taiwanese Depression Questionnaire (TDQ). Subjects with TDQ scores 19-54 (correlated with clinically significant depressive symptoms) and those with scores 15-18 had higher 3-year mortality rates than the two groups with lower scores (40.0%, 46.7%, 16.0% and 19.6%, p = 0.021, ANOVA). Affective and cognitive symptoms, including sadness, tenseness, indecisiveness and low self-confidence, and one somatic item (bodily discomfort) were associated with mortality. Affective and cognitive symptoms affected quality of life more than somatic symptoms. The somatic subscale was associated with female gender, low income and education, dialysis vintage, and low serum creatinine and albumin levels, whereas the affective and cognitive subscale was associated with less education and a low serum albumin level. In conclusion, affective and cognitive symptoms of depression may better predict long-term mortality in patients undergoing chronic hemodialysis than somatic symptoms. ? 2018 The Author(s). |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85045457434&doi=10.1038%2fs41598-018-24267-5&partnerID=40&md5=4073541b38653bbe82be88e65299699a https://scholars.lib.ntu.edu.tw/handle/123456789/578403 |
ISSN: | 2045-2322 | DOI: | 10.1038/s41598-018-24267-5 | SDG/關鍵字: | adult; adverse event; aged; anxiety; cognition; depression; female; heart failure; hemodialysis; human; male; middle aged; mortality; pathophysiology; prognosis; psychological rating scale; quality of life; questionnaire; Adult; Aged; Anxiety; Cognition; Depression; Female; Heart Failure; Humans; Male; Middle Aged; Prognosis; Psychiatric Status Rating Scales; Quality of Life; Renal Dialysis; Surveys and Questionnaires |
顯示於: | 醫學系 |
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