https://scholars.lib.ntu.edu.tw/handle/123456789/580249
標題: | The emerging epidemic of estrogen-related cancers in young women in a developing Asian country | 作者: | CHING-HUNG LIN Chen Y.-C. CHUN-JU CHIANG YEN-SHEN LU KUAN-TING KUO CHIUN-SHENG HUANG WEN-FANG CHENG Lai M.-S. You S.-L. ANN-LII CHENG |
公開日期: | 2012 | 卷: | 130 | 期: | 11 | 起(迄)頁: | 2629-2637 | 來源出版物: | International Journal of Cancer | 摘要: | The incidence of breast and genital tract cancers is increasing among Taiwanese women, but the age specificity and histopathological features of these cancers have not been determined. We used a descriptive epidemiological method and data from the Taiwan Cancer Registry (1979-2007) to examine secular trends in the age-specific incidences of female breast cancer, three major female genital tract cancers and the histopathological subtypes of these cancers. Age-specific incidence rates in the United States (1978-2002) were used as an external reference, and the incidence rates of all malignancies and of malignant brain tumors were used as internal references. We found that age-adjusted incidence rates of female breast, uterine, and ovarian cancers increased in Taiwan from 1979 to 2007, whereas the incidence of cervical cancer decreased after 1998. The largest increase was observed for ductal and lobular carcinomas of the breast and endometrioid carcinomas of the uterus and ovary in women ?55 years, all of these tumors show a high prevalence of hormone receptor expressions. In addition, hormone-receptor-positive rates of breast cancer were uniquely higher in younger, as opposed to older, Taiwanese women. These findings indicate that estrogen-related cancers rapidly emerge in young women in Taiwan and that incidence rates are catching up with that of women living in the United States. Copyright ? 2011 UICC. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84859156639&doi=10.1002%2fijc.26249&partnerID=40&md5=543f1ec0f2011c554f742070ef8e5900 https://scholars.lib.ntu.edu.tw/handle/123456789/580249 |
DOI: | 10.1002/ijc.26249 | SDG/關鍵字: | estrogen; hormone receptor; adolescent; adult; age distribution; aged; article; Asian; brain cancer; breast cancer; cancer epidemiology; cancer incidence; cancer localization; cancer registry; child; controlled study; developing country; disease association; endometrioid carcinoma; epidemic; female; female genital tract cancer; histopathology; human; lung carcinoma; major clinical study; malignant neoplastic disease; ovary cancer; preschool child; prevalence; priority journal; protein expression; school child; trend study; uterus cancer; Brain Neoplasms; Breast Neoplasms; Female; Genital Neoplasms, Female; Humans; Incidence; Receptors, Estrogen; Receptors, Progesterone; Taiwan; Time Factors |
顯示於: | 醫學系 |
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