https://scholars.lib.ntu.edu.tw/handle/123456789/581539
標題: | Development of a microfluidic platform for induction of angiogenesis from a vascularized microtissue | 作者: | Yang W.-C Lin C.-Y WEI-WEN LIU Li P.-C Hsu Y.-H. PAI-CHI LI |
關鍵字: | Drug delivery; Microchannels; Tumors; Angiogenesis; Angiogenic process; Micro-chambers; Microfluidic chip; Microfluidic platforms; Vasculature; Vasculogenic; Vessel networks; Microfluidics | 公開日期: | 2019 | 起(迄)頁: | 1516-1517 | 來源出版物: | 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 | 摘要: | In this paper, we report a new microfluidic approach to stimulate both vasculogenic and angiogenic processes in one microfluidic chip. This microfluidic platform can first develop a vascularized microtissue by vasculogenic process in one microchamber followed by stimulating angiogentic sprouting process from these pre-existing vasculature and growing into an adjacent microchamber to form vessels in a stroma or tumor microtissue. Experimental results verified that angiogenic process and tumor-angiogenic process can be induced in this microfluidic platform. This design can provide a more realistic angiogenic vessel network for the application of drug delivery and organ-on-a-chip. ? 2019 CBMS-0001. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85094981180&partnerID=40&md5=148113e9b784b38416dba76163e02452 https://scholars.lib.ntu.edu.tw/handle/123456789/581539 |
顯示於: | 生醫電子與資訊學研究所 |
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