https://scholars.lib.ntu.edu.tw/handle/123456789/582144
標題: | Hepatitis B viral genotype in Taiwanese patients with acute hepatitis B | 作者: | YI-WEN HUANG Lin C.-L. PEI-JER CHEN Lai M.-Y. JIA-HORNG KAO DING-SHINN CHEN |
公開日期: | 2008 | 出版社: | H.G.E. Update Medical Publishing Ltd. | 卷: | 55 | 期: | 82-83 | 起(迄)頁: | 633-635 | 來源出版物: | Hepato-Gastroenterology | 摘要: | Background/Aims: The correlation of HBV genotype with clinical outcome has been recognized in chronic hepatitis B patients. However, there are few reports on the distribution and clinical significance of HBV genotypes in acute hepatitis B patients. Methodology: Nineteen acute hepatitis B patients were identified and their HBV genotypes were determined. The serological and clinical data were thus compared between patients with different HBV genotypes. Results: Two HBV genotypes (B and C) were found in the patients. Genotype B was more predominant than genotype C (12 vs. 7). The age, serum alanine aminotransferase level, serum alpha-fetoprotein level, and serum HBV DNA level were not significantly different between patients infected with genotype B or C. None of them had persistent HBsAg for longer than 6 months. Conclusions: Genotype B predominates in acute hepatitis B patients in Taiwan; however, the clinical features between genotype B and genotype C patients are comparable. ? H.G.E. Update Medical Publishing S.A. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84984549249&partnerID=40&md5=73da02f5cdd160ea9150ffac97199456 https://scholars.lib.ntu.edu.tw/handle/123456789/582144 |
ISSN: | 0172-6390 | SDG/關鍵字: | alanine aminotransferase; hepatitis B surface antigen; acute hepatitis; adult; alanine aminotransferase blood level; article; controlled study; female; genotype; groups by age; hepatitis B; Hepatitis B virus; human; male; priority journal; serology; Taiwan; viral genetics |
顯示於: | 臨床醫學研究所 |
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