https://scholars.lib.ntu.edu.tw/handle/123456789/584516
標題: | Association between Testicular Cancer and Epididymoorchitis: A Population-Based Case-Control Study | 作者: | Kao L.-T. Lin H.-C. Chung S.-D. CHAO-YUAN HUANG |
公開日期: | 2016 | 出版社: | Nature Publishing Group | 卷: | 6 | 起(迄)頁: | 23079 | 來源出版物: | Scientific Reports | 摘要: | Even though epididymoorchitis and testicular cancer (TC) may have similar pathophysiological pathways, no prior study has attempted to determine the association between these two diseases. This case-control study investigated the relationship between TC and prior epididymoorchitis by using a large population-based database. We used the Taiwan Longitudinal Health Insurance Database 2005 to select 372 patients who had received a diagnosis of TC and 3,720 age-matched controls without TC. We found that of the total sample of 4,092 patients, 53 (1.3%) had received a diagnosis of epididymoorchitis prior to the index date. Patients with TC had a higher prevalence of prior epididymoorchitis than that of patients without TC (11.0% vs. 0.3%, p < 0.001). Conditional logistic regression showed that prior epididymoorchitis was significantly associated with TC (crude OR = 38.24, 95% CI = 19.91-73.46). The association remained statistically significant even after adjustment for the other variables (OR = 47.17, 95% CI = 23.83-93.40). This study showed that patients with TC have higher odds of prior epididymoorchitis than do those without TC even after adjustment for potential confounders. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84960952109&doi=10.1038%2fsrep23079&partnerID=40&md5=e9a994dc6f2aa1ccf56d942fb8f40517 https://scholars.lib.ntu.edu.tw/handle/123456789/584516 |
ISSN: | 2045-2322 | DOI: | 10.1038/srep23079 | SDG/關鍵字: | adolescent; adult; case control study; comorbidity; epididymitis; factual database; health insurance; human; male; middle aged; odds ratio; orchitis; prevalence; statistical model; statistics and numerical data; Taiwan; Testicular Neoplasms; young adult; Adolescent; Adult; Case-Control Studies; Comorbidity; Databases, Factual; Epididymitis; Humans; Insurance, Health; Logistic Models; Male; Middle Aged; Odds Ratio; Orchitis; Prevalence; Taiwan; Testicular Neoplasms; Young Adult |
顯示於: | 醫學系 |
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