https://scholars.lib.ntu.edu.tw/handle/123456789/584541
標題: | Correlation between bladder pain syndrome/interstitial cystitis and pelvic inflammatory disease | 作者: | Chung S.-D. Chang C.-H. Hung P.-H. Chung C.-J. Muo C.-H. CHAO-YUAN HUANG |
公開日期: | 2015 | 出版社: | Lippincott Williams and Wilkins | 卷: | 94 | 期: | 46 | 起(迄)頁: | e1878 | 來源出版物: | Medicine (United States) | 摘要: | Pelvic inflammatory disease (PID) has been investigated in Western countries and identified to be associated with chronic pelvic pain and inflammation. Bladder pain syndrome/interstitial cystitis (BPS/IC) is a complex syndrome that is significantly more prevalent in women than in men. Chronic pelvic pain is a main symptom of BPS/IC, and chronic inflammation is a major etiology of BPS/IC. This study aimed to investigate the correlation between BPS/IC and PID using a populationbased dataset. We constructed a case-control study from the Taiwan National Health Insurance program. The case cohort comprised 449 patients with BPS/IC, and 1796 randomly selected subjects (about 1:4 matching) were used as controls. A Multivariate logistic regression model was constructed to estimate the association between BPS/IC and PID. Of the 2245 sampled subjects, a significant difference was observed in the prevalence of PID between BPS/IC cases and controls (41.7% vs 15.4%, P<0.001). Multivariate logistic regression analysis revealed that the odds ratio (OR) for PID among cases was 3.69 (95% confidence interval [CI]: 2.89-4.71). Furthermore, the ORs for PID among BPS/IC cases were 4.52 (95% CI: 2.55-8.01), 4.31 (95% CI: 2.91-6.38), 3.00 (95% CI: 1.82-4.94), and 5.35 (95% CI: 1.88-15.20) in the <35, 35-49, 50-64, and >65 years age groups, respectively, after adjusting for geographic region, irritable bowel syndrome, and hypertension. Joint effect was also noted, specifically when patients had both PID and irritable bowel disease with OR of 10.5 (95% CI: 4.88-22.50). This study demonstrated a correlation between PID and BPS/IC. Clinicians treating women with PID should be alert to BPS/IC-related symptoms in the population. ? 2015 Wolters Kluwer Health, Inc. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84948660562&doi=10.1097%2fMD.0000000000001878&partnerID=40&md5=724ad0e35af7ec85ca8ea9778d9493a1 https://scholars.lib.ntu.edu.tw/handle/123456789/584541 |
ISSN: | 0025-7974 | DOI: | 10.1097/MD.0000000000001878 | SDG/關鍵字: | adult; Article; controlled study; correlational study; cystalgia; disease association; female; geographic distribution; groups by age; human; hypertension; interstitial cystitis; irritable colon; major clinical study; national health insurance; pelvic inflammatory disease; population based case control study; prevalence; priority journal; aged; case control study; complication; Cystitis, Interstitial; factual database; longitudinal study; middle aged; pelvic inflammatory disease; risk factor; statistical model; very elderly; Adult; Aged; Aged, 80 and over; Case-Control Studies; Cystitis, Interstitial; Databases, Factual; Female; Humans; Logistic Models; Longitudinal Studies; Middle Aged; Pelvic Inflammatory Disease; Risk Factors |
顯示於: | 醫學系 |
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