Validation of a Post-Transplant Lymphoproliferative Disorder Risk Prediction Score and Derivation of a New Prediction Score Using a National Bone Marrow Transplant Registry Database
Journal
The oncologist
Date Issued
2021-09-10
Author(s)
Hsu, Tzu-Chun
Kuo, Chia-Chih
Liu, Michael A
Abdelfattah, Ahmed M
Chang, Chia-Na
Li, Chi-Cheng
Wu, Kang-Hsi
Chen, Tsung-Chih
Gau, Jyh-Pyng
Wang, Po-Nan
Liu, Yi-Chang
Chiou, Lun-Wei
Lee, Ming-Yang
Li, Sin-Syue
Chao, Tsu-Yi
Abstract
We externally validated Fujimoto's post-transplant lymphoproliferative disorder (PTLD) scoring system for risk prediction by using the Taiwan Blood and Marrow Transplant Registry Database (TBMTRD) and aimed to create a superior scoring system using machine learning methods.
Subjects
Hematopoietic cell transplant; Least absolute shrinkage and selection operator; Post-transplant lymphoproliferative disorder; Predictive scoring system
Other Subjects
busulfan; cyclophosphamide; fludarabine; thymocyte antibody; acute lymphoblastic leukemia; acute myeloid leukemia; adult; aplastic anemia; Article; bone marrow transplantation; chronic lymphatic leukemia; chronic myeloid leukemia; coronary artery bypass graft; demography; diagnostic procedure; female; graft versus host reaction; hematologic disease; hematopoietic stem cell transplantation; hematopoietic system malignancy; Hodgkin disease; human; human cell; human experiment; immunosuppressive treatment; laboratory test; major clinical study; male; multiple myeloma; myelodysplastic syndrome; myeloproliferative disorder; nonhodgkin lymphoma; patient registry; peripheral blood stem cell; posttransplant lymphoproliferative disease; prediction; prospective study; pulmonary veno-occlusive disease; receiver operating characteristic; risk assessment; scoring system; sensitivity and specificity; survival; thalassemia major; umbilical cord blood; validation study; adverse event; hematopoietic stem cell transplantation; lymphoproliferative disease; methodology; register; risk factor; Hematopoietic Stem Cell Transplantation; Humans; Lymphoproliferative Disorders; Registries; Research Design; Risk Factors
Type
journal article