https://scholars.lib.ntu.edu.tw/handle/123456789/586037
標題: | Tyrosine Kinase Inhibitors and Vascular Adverse Events in Patients with Chronic Myeloid Leukemia: A Population-Based, Propensity Score-Matched Cohort Study | 作者: | Chen, Mei-Tsen Huang, Shih-Tsung Lin, Chih-Wan BOR-SHENG KO WEN-JONE CHEN HUAI-HSUAN HUANG FEI-YUAN HSIAO |
關鍵字: | Chronic myeloid leukemia; Tyrosine kinase inhibitors; Vascular adverse events | 公開日期: | 21-八月-2021 | 來源出版物: | The oncologist | 摘要: | Tyrosine kinase inhibitors (TKIs) have shown long-term survival benefits in patients with chronic myeloid leukemia (CML). Nevertheless, significant concern has been raised regarding long-term TKI-associated vascular adverse events (VAEs). The objective of this retrospective cohort study was to investigate the incidence of VAEs in Taiwanese patients with CML treated with different TKIs (imatinib, nilotinib, and dasatinib) as well as potential risk factors. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/586037 | ISSN: | 10837159 | DOI: | 10.1002/onco.13944 | SDG/關鍵字: | acetylsalicylic acid; anticoagulant agent; antidiabetic agent; antihypertensive agent; antilipemic agent; antithrombocytic agent; cyclooxygenase 2 inhibitor; dasatinib; dihydroergotoxine; Ginkgo biloba extract; hydroxyurea; imatinib; neuroleptic agent; nicametate; nilotinib; pentoxifylline; piracetam; protein kinase inhibitor; adult; adverse drug reaction; Article; cerebrovascular disease; Charlson Comorbidity Index; chronic lung disease; chronic myeloid leukemia; clinical outcome; cohort analysis; congestive heart failure; dementia; diabetes mellitus; dyslipidemia; female; heart infarction; hormone substitution; human; hypertension; incidence; ischemic heart disease; ischemic stroke; kidney disease; liver disease; major clinical study; male; middle aged; peptic ulcer; peripheral occlusive artery disease; peripheral vascular disease; propensity score; retrospective study; rheumatic disease; risk factor; Taiwanese; venous thromboembolism; aged; Aged; Cohort Studies; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Propensity Score; Protein Kinase Inhibitors; Retrospective Studies |
顯示於: | 醫學院附設醫院 (臺大醫院) |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。