https://scholars.lib.ntu.edu.tw/handle/123456789/586120| Title: | Etiology-associated heterogeneity in acute respiratory distress syndrome: a retrospective cohort study | Authors: | SHENG-YUAN RUAN CHUN-TA HUANG YING-CHUN CHIEN CHUN-KAI HUANG JUNG-YIEN CHIEN LU-CHENG KUO PING-HUNG KUO SHIH-CHI KU HUEY-DONG WU |
Keywords: | Acute respiratory distress syndrome; Heterogeneity; Phenotype; Pneumonia; Respiratory failure; Sepsis | Issue Date: | 31-May-2021 | Journal Volume: | 21 | Journal Issue: | 1 | Source: | BMC pulmonary medicine | Abstract: | Heterogeneity in acute respiratory distress syndrome (ARDS) has led to many statistically negative clinical trials. Etiology is considered an important source of pathogenesis heterogeneity in ARDS but previous studies have usually adopted a dichotomous classification, such as pulmonary versus extrapulmonary ARDS, to evaluate it. Etiology-associated heterogeneity in ARDS remains poorly described. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/586120 | ISSN: | 1471-2466 | DOI: | 10.1186/s12890-021-01557-9 | SDG/Keyword: | [SDGs]SDG3 albumin; C reactive protein; D dimer; lactate dehydrogenase; lactic acid; biological marker; fibrin degradation product; fibrin fragment D; adult; adult respiratory distress syndrome; aged; Article; artificial ventilation; bacterial pneumonia; blood clotting; cohort analysis; controlled study; disease association; disease classification; extra pulmonary sepsis; female; genetic heterogeneity; Horowitz index; human; inflammation; intensive care unit; major clinical study; male; mortality; mortality rate; pathogenesis; pneumonia; retrospective study; sepsis; Sequential Organ Failure Assessment Score; shock; thrombocyte; bacterial infection; complication; lung gas exchange; metabolism; middle aged; organ dysfunction score; respiratory distress syndrome; respiratory failure; statistical model; very elderly; Aged; Aged, 80 and over; Bacterial Infections; Biomarkers; Female; Fibrin Fibrinogen Degradation Products; Humans; Linear Models; Male; Middle Aged; Organ Dysfunction Scores; Pneumonia; Pulmonary Gas Exchange; Respiratory Distress Syndrome; Respiratory Insufficiency; Retrospective Studies; Sepsis |
| Appears in Collections: | 醫學系 |
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