Adjuvant intravitreal bevacizumab injection for choroidal and orbital metastases of refractory invasive ductal carcinoma of the breast
Journal
Medicina (Lithuania)
Journal Volume
57
Journal Issue
5
Date Issued
2021
Author(s)
Abstract
The efficacy of combined intravitreal bevacizumab injection with systemic chemotherapy, palliative radiotherapy, and hormonal therapy to treat choroidal and orbital metastases is not known. Herein, we report the case of a 48-year-old woman with systemic chemotherapy-resistant choroidal and orbital metastases of the left eye originating from a stage IV invasive ductal carcinoma of the left breast. We describe the addition of a single intravitreal injection of bevacizumab in addition to treatment with systemic chemotherapy, hormonal therapy, and palliative radiotherapy. The patient’s outcome at 6-month follow-up was favorable, as the metastatic lesion reduced in size and visual acuity improved. Combined treatment with intravitreal bevacizumab injection, systemic chemotherapy, palliative radiotherapy, and hormonal therapy can resolve ocular metastatic lesions originating from breast cancers. ? 2021 by the authors. Licensee MDPI, Basel, Switzerland.
Subjects
Bevacizumab; Breast cancer; Choroidal metastasis; Intravitreal injection; Orbital metastasis
SDGs
Other Subjects
angiogenesis inhibitor; bevacizumab; case report; female; human; intravitreal drug administration; middle aged; optical coherence tomography; Paget nipple disease; Angiogenesis Inhibitors; Bevacizumab; Carcinoma, Ductal; Female; Humans; Intravitreal Injections; Middle Aged; Tomography, Optical Coherence
Publisher
MDPI AG
Type
journal article